Abstract
Introduction
The current pool of organs available for transplantation does not cover requirements, for this reason non-standard risk donors need to be incorporated into the pool. In this way, donors with small renal tumour are considered for transplantation after bench tumour excision. The aim of our study was to analyse our experience in using these grafts for transplantation.
Materials and methods
Retrospective analysis from our prospective accrued database of donors with incidental renal mass used for kidney transplantation between January 2007 and August 2018.
Results
Twenty kidney transplantations were performed, thirteen cases received the affected kidney (after tumour removal) and seven the contralateral kidney; from six living and eleven deceased donors. Donor and recipient median age was 58 years (range 22–82) and 56.5 years (range 38–74), respectively. Mean tumour diameter was 12.7 mm (SD 9.5). Tumours resulted in two benign lesions and fifteen renal cell carcinoma. Surgical margins were negative. Two cases presented with bleeding after reperfusion was solved without repercussion. One case presented with immediate vein thrombosis. None of them present delayed graft function. After a 69 month follow-up none of the donors or the recipients presented tumour recurrence.
Conclusions
Kidneys with small incidental tumours seem to be a good option for kidney transplantation in selected patients after bench surgery excision with good functional and oncologic results. More studies and longer follow-up are needed to confirm these results.
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Abbreviations
- DCD:
-
Donation after death determined by circulatory criteria
- ECD:
-
Expanded-criteria donors
- RCC:
-
Renal cell carcinoma
- ESRD:
-
End stage renal disease
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Protocol/project development: MM, AS and AA. Data collection or management: AS, MP, CM, DP. Data analysis: MM, AS, LLP, FD. Manuscript writing/editing: MM, AS, NE.
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Musquera, M., Sierra, A., Diekmann, F. et al. Increasing kidney grafts for transplantation. World J Urol 39, 2795–2800 (2021). https://doi.org/10.1007/s00345-020-03463-x
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DOI: https://doi.org/10.1007/s00345-020-03463-x