Abstract
Purpose
To compare different extractions routes for robot-assisted living donor nephrectomy in terms of post-operative pain and renal function recovery.
Methods
Live donor kidney transplantation data from our institution were reviewed from November 2011 to March 2017. Postoperative pain was estimated using cumulative painkillers consumption. Variables were compared between the 3 groups with ANOVA for continuous data, χ2 test for categorial data. A survival analysis with Kaplan–Meier curve assessing time to transplant recipient nadir was performed to compare the renal function recovery.
Results
Sixty-three RLDN were performed (23 iliac, 23 vaginal and 17 umbilical extractions). There was no significant difference between the three groups in terms of operative time, blood lost, warm ischemia time, cumulative painkiller consumption and renal function recovery time. Postoperative complications for Umbilical, Vaginal and Iliac were, respectively, of 0, 3 and 1. No major difference was found between the 3 groups beside a slightly longer hospital stay in the iliac group.
Conclusion
Iliac incision might impact post-operative pain with a moderate but significant longer hospital stay. Vaginal extraction is an option when cosmetic outcomes present a real demand. The three options appeared to be safe and should be discussed with the patient in regard of the surgeon experience.
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References
Murray G, Holden R (1954) Transplantation of kidneys, experimentally and in human cases. Am J Surg 87:508–515
Ratner LE, Ciseck LJ, Moore RF, Cigarroa FG, Kaufman HS, Kavoussi LR (1995) Laparoscopic live donor nephrectomy. Transplantation 60:1047–1097
Musquera M, Peri L, Izquierdo L, Campillo P, Ribal MJ, Alcaraz A (2011) Pioneer experience in Spain with LESS nephrectomy in living donor [in Spanish]. Actas Urol Esp 35(559):e62
Horgan S, Vanuno D, Sileri P et al (2002) Robotic-assisted laparoscopic donor nephrectomy for kidney transplantation. Transplantation 73:1474–1479
Wadström J, Lindström P (2002) Hand-assisted retroperitoneoscopic living-donor nephrectomy: initial 10 cases. Transplantation 73:1839–1840
Kok NFM, Lind MY, Hansson BME, Pilzecker D, Mertenszur Borg IR, Knipscheer BC et al (2006) Comparison of laparoscopic and mini incision open donor nephrectomy: single blind, randomized clinical trial. BMJ 333:221
Simforoosh N, Basiri A, Shakhssalim N, Gooran S, Tabibi A, Khosdel A et al (2012) Long-term graft function in a randomized clinical trial comparing laparoscopic versus open donor nephrectomy. Exp Clin Transplant 10:428–443
Nicholson ML, Elwell R, Kaushik M, Bagul A, Hosgood SA (2011) Health-related quality of life after living donor nephrectomy: a randomized controlled trial of laparoscopic versus open nephrectomy. Transplantation 91:457–461
Nicholson ML, Kaushik M, Lewis GR, Brook NR, Bagul A, Kay MD et al (2010) Randomized clinical trial of laparoscopic versus open donor nephrectomy. Br J Surg 97:21–28
Andersen MH, Mathisen L, Oyen O, Edwin B, Digernes R, Kvarstein G et al (2006) Postoperative pain and convalescence in living kidney donorsdlaparoscopic versus open donor nephrectomy: a randomized study. Am J Transplant 6:1438–1443
Bird V, Au J, Sandman Y, De Los SR, Ayyathurai R, Shields J (2009) Comparison of different extraction sites used during laparoscopic radical nephrectomy. Urology 181:1565–1570
Galvani CA, Garza U, Leeds M et al (2012) Single-incision robotic-assisted living donor nephrectomy: case report and description of surgical technique. Transpl Int 25:89–92
Oberholzer J, Tzvetanov I, Mele A et al (2010) Laparoscopic and robotic donor pancreatectomy for living donor pancreas and pancreas-kidney transplantation. J Hepatobiliary Pancreat Sci 17:97–100
Pietrabissa A, Abelli M, Spinillo A et al (2010) Robotic-assisted laparoscopic donor nephrectomy with transvaginal extraction of the kidney. Am J Transplant 10:2708–2711
Gorodner V, Horgan S, Galvani C et al (2006) Routine left robotic-assisted laparoscopic donor nephrectomy is safe and effective regardless of the presence of vascular anomalies. Transpl Int 19:636–640
Horgan S, Galvani C, Gorodner MV et al (2007) Effect of robotic assistance on the ‘‘learning curve’’ for laparoscopic hand-assisted donor nephrectomy. SurgEndosc 21:1512–1517
Guner Can M, Ozcan P, Hatipoglu S, Cavdaroglu O, Hatipoglu F, Berber I et al (2015) Laparoscopic-assisted live donor ne-phrectomy: a comparison of conventional and transvaginal routesfor kidney extraction. Ann Transplant 20:634–638
Kishore TA, Shetty A, Balan T, John MM, Iqbal M, Jose J et al (2013) Laparoscopic donor nephrectomy with transvaginalextraction:initial experience of 30 cases. J Endourol 27:1361–1365
Alcaraz A, Musquera M, Peri L, Izquierdo L, García-Cruz E, Huguet J et al (2011) Feasibility of transvaginal natural orificetransluminal endoscopic surgeryeassisted living donornephrectomy: is kidney vaginal delivery the approach of the future? Eur Urol 59:1019–1025
Canes D, Berger A, Aron M et al (2010) Laparo-endoscopic single site (LESS) versus standard laparoscopic left donor nephrectomy:matched-pair comparison. Eur Urol 57:95–101
Barth RN, Phelan MW, Goldschen L, Munivenkatappa RB, Jacobs SC, Bartlett ST, Philosophe B (2013) Single-port donor nephrectomy provides improved patient satisfaction and equivalent outcomes. Ann Surg 257(3):527–533
Li M, Cao B, Gong R, Sun D, Zhang P, Jiang X et al (2018) Randomized trial of umbilical incisional hernia in high-risk patients: extraction of gallbladder through subxiphoid port vs. umbilical port after laparoscopic cholecystectomy. Wideochirurgia Inne Tech Maloinwazyjne Videosurg Miniinvasive Tech 13(3):342–349
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MA project development, data collection, manuscript writing. CC data collection. JBATDC data collection and management, data analysis, data analysis. JC data collection. RY data collection. AH data collection. DV data collection. PG data collection. MM data collection. TL data collection. PLC data collection. LS project development. AdlT project development. AI project development, manuscript writing and editing.
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Abdessater, M., Champy, C.M., da Costa, J.B. et al. Comparison of the iliac, vaginal and umbilical graft extraction in robot-assisted laparoscopic living donor nephrectomy. World J Urol 39, 2783–2788 (2021). https://doi.org/10.1007/s00345-020-03462-y
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DOI: https://doi.org/10.1007/s00345-020-03462-y