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Table 4 Uni- and multivariate logistic regression on risk of prostate cancer with ISUP Grade Group ≥ 2

From: Effect of information on prostate biopsy history on biopsy outcomes in the era of MRI-targeted biopsies

  Univariate analysis Multivariate analysis
  OR 95% CI OR 95% CI
Using MRI-targeted biopsies
 Previous biopsy, years/n 0.47 0.30 0.74 0.38 0.20 0.71
 Age, years 0.98 0.95 0.99 1.00 0.97 1.03
 PSA, total 1.08 1.05 1.12 1.01 0.94 1.09
 PSA density, ng/ml/cc (100) 1.07 1.05 1.09 1.04 1.01 1.07
 PI-RADS score, ≤ 2–5 5.10 3.87 6.72 4.58 3.32 6.31
 Digital rectal examination, pathological, 1/0 4.20 2.83 6.23 1.48 0.85 2.57
Using systematic biopsies
 Previous biopsy, years/n 0.28 0.17 0.46 0.25 0.13 0.49
 Age, years 1.00 0.98 1.02 1.00 0.98 1.03
 PSA, total 1.08 1.04 1.11 1.03 0.96 1.10
 PSA density, ng/ml/cc (100) 1.06 1.04 1.08 1.06 1.03 1.09
 Digital rectal examination, pathological, 1/0 5.26 3.52 7.86 4.32 2.71 6.90