Abstract
Purpose
Few studies mention the necessity of antimicrobial prophylaxis (AMP) for transurethral resection of bladder tumor (TURBT) and the risk factors for postoperative urinary tract infections (UTIs) after TURBT. To evaluate the necessity of AMP and to detect the risk of UTIs, we examined the perioperative clinical factors.
Methods
687 patients who underwent TURBT between 2006 and 2017 at Hiroshima Prefectural Hospital were examined retrospectively. We defined the postoperative UTIs as febrile UTIs (≥ 38 °C). The AMP for the TURBT that we used was mostly cephalosporin generation 1. The association between the perioperative clinical/pathological factors and postoperative UTIs was assessed by logistic regression retrospectively.
Results
21 patients (3.1%) suffered from postoperative UTIs, and almost all of them were successfully treated with the immediate administration of antibiotics. Univariate analysis showed that past pelvic radiotherapy (p = 0.024, odds ratio (OR) 6.00), tumor size (≥ 2cm) (p = 0.008, OR 3.38), age (≥ 75 years) (p = 0.036, OR 2.65), preoperative hospital stay (≥ 5 days) (p = 0.017, OR 3.76), asymptomatic pyuria (p = 0.038, OR 2.54) and bacteriuria (p = 0.044, OR 2.97) were all associated with postoperative UTIs.
Conclusions
We demonstrated that AMP was effective for patients who underwent TURBT, and history of pelvic radiotherapy, high age, preoperative hospital stay and a certain tumor size were the risk factors as well as pyuria and bacteriuria of postoperative UTIs.
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Abbreviations
- TURBT:
-
Transurethral resection of bladder tumors
- AMP:
-
Antimicrobial prophylaxis
- UTIs:
-
Urinary tract infections
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YK: protocol/project development, data management, data analysis, and manuscript writing. AG: manuscript editing. KY: data collection. SO: manuscript editing. MK: protocol/project development.
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Kohada, Y., Goriki, A., Yukihiro, K. et al. The risk factors of urinary tract infection after transurethral resection of bladder tumors. World J Urol 37, 2715–2719 (2019). https://doi.org/10.1007/s00345-019-02737-3
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DOI: https://doi.org/10.1007/s00345-019-02737-3