World Journal of Urology

, Volume 36, Issue 7, pp 1103–1109 | Cite as

A new treatment of female stress urinary incontinence with vaginal antetheca–retropubic space mesh repair surgery: a clinical trial

  • Geping Yin
  • Zheng Yuan
  • Juan Li
  • Jing Liang
  • Aifang Wu
  • Na Liu
Original Article
  • 72 Downloads

Abstract

Purpose

To investigate the short- and medium-term effect of vaginal antetheca submucosal-retropubic space with mesh repair through the implantation of organic patch (shortly as new-style vaginal mesh repair) in the treatment of patients with stress urinary incontinence (SUI).

Methods

This was a clinical prospective single arm study in a tertiary grade hospital (General Hospital of Jinan Military Region, Jinan, China). From January 2009 to December 2014, 316 female patients were enrolled. 316 female patients with stress urinary incontinence (SUI) underwent the surgery. The treatment effect was evaluated using the urinary incontinence questionnaire (ICIQ-SF), urine pad test and coughing test. The perioperative and postoperative complications were also evaluated. The results were compared with 1-year cure rates of Burch retropubic urethropexy (Burch) and tension-free vaginal tape (TVT) procedure.

Results

The mean follow-up period was 25 ± 12 months. The success rate of the new surgical technique was 94.0% (297/316) at 1 month, and 91.5% (289/316) at 1-year postoperation. The ICIQ-SF score significantly decreased at the 1-year follow-up (P < 0.01). There was no significant difference in the 1-year cure rate when compared with the Burch and TVT procedures (P > 0.05). The rates of perioperative urinary tract irritation and mesh exposure were 9.5% (30/316) and 5.38% (17/316), respectively, and no serious complications were found.

Conclusions

The surgery demonstrated favorable short-term and medium-term treatment effects. Given its advantages of being minimally invasive, cost efficient and requiring only local anesthesia, this new surgical technique has a potential for broader clinical application.

ClinicalTrials.gov ID

NCT02934490.

Keywords

Stress urinary incontinence New vaginal anterior wall mesh repair Minimally invasive surgery Efficacy 

Notes

Author contribution

GP Yin: protocol/project development, data collection and manuscript writing. Z Yuan: data collection. J Li: data management. J Liang, AF Wu, and N Liu: data analysis.

Compliance with ethical standards

Conflict of interest

None of the authors has a financial interest in any of the products, devices, or drugs mentioned in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Geping Yin
    • 1
  • Zheng Yuan
    • 1
  • Juan Li
    • 1
  • Jing Liang
    • 1
  • Aifang Wu
    • 1
  • Na Liu
    • 1
  1. 1.Department of Obstetrics and GynecologyJinan Military General HospitalJinanChina

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