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World Journal of Urology

, Volume 36, Issue 4, pp 585–593 | Cite as

A randomized, prospective study of laparoendoscopic single-site plus one-port versus mini laparoscopic technique for live donor nephrectomy

  • Kyu Won Lee
  • Sae Woong Choi
  • Yong Hyun Park
  • Woong Jin Bae
  • Yong Sun Choi
  • U-Syn Ha
  • Sung-Hoo Hong
  • Ji Youl Lee
  • Sae Woong Kim
  • Hyuk Jin Cho
Original Article

Abstract

Purpose

To compare the clinical outcomes of laparoendoscopic single-site plus one-port donor nephrectomy (LESSOP-DN) and mini laparoscopic donor nephrectomy (MLDN).

Methods

A prospective randomized controlled trial was conducted from December 2014 to February 2016 in donors scheduled for left donor nephrectomy. Donor and recipient demographics and clinical outcomes including pain scores and questionnaires (BIQ: body image questionnaire, SF-36, patient-reported overall convalescence) were also compared.

Results

A total of 121 eligible donors were recruited, of which 99 donors who were scheduled to undergo an operation on their left side were randomized into LESSOP-DN (n = 50) and MLDN (n = 49) groups. There were no significant demographic differences between the two groups. The renal extraction time in the LESS-DN group was shorter than that in the MLDN group (75.89 ± 13.01 vs. 87.31 ± 11.38 min, p < 0.001). Other perioperative parameters and complication rates were comparable between the two groups. The LESSOP-DN group had a smaller incision length than the MLDN group (4.89 ± 0.68 vs. 6.21 ± 1.11 cm, p < 0.001), but cosmetic scores and body image scores were similar in the two groups (p = 0.905, 0.217). Donor quality of life (SF-36) and recovery and satisfaction data were comparable between the two groups. Delayed graft function (DGF) occurred in one recipient undergoing MLDN procedure (2.1%) and progressed to graft failure.

Conclusions

There were no differences in cosmetic satisfaction between groups despite the smaller incision size of LESSOP-DN. Safety parameters and subjective measures of postoperative morbidity were similar between the two groups.

Keywords

Kidney transplantation Laparoscopy Minimally invasive surgery 

Abbreviations

LESSOP-DN

Laparoendoscopic single-site plus one-port donor nephrectomy

MLDN

Mini laparoscopic donor nephrectomy

BIQ

Body image questionnaire

DGF

Delayed graft function

SF-36

RAND 36-item short-form health survey questionnaire

QoL

Quality of life

WIT

Warm ischemia time

EBL

Estimated blood loss

LOS

Length of stay

HALDN

Hand-assisted laparoscopic donor nephrectomy

Notes

Author contributions

KWL: data collection and analysis, manuscript writing. SWC: protocol development, data collection. YHP: data collection. WJB: data collection. YSC: data management. UH: data management. SH: data analysis. JYL: manuscript editing. SWK: manuscript editing. HJC: protocol and project development, manuscript editing

Funding

None.

Compliance with ethical standards

Conflict of interest

Kyu Won Lee, Sae Woong Choi, Yong Hyun Park, Woong Jin Bae, Yong Sun Choi, U-Syn Ha, Sung-Hoo Hong, Ji Youl Lee, Sae Woong Kim and Hyuk Jin Cho have no conflicts of interests or financial ties to disclose.

Ethical standards

All human studies have been approved by the appropriate ethics committee and have, therefore, been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. This study has been approved by our institutional review board (KC15EISI0015).

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Urology, Seoul St. Mary’s Hospital, College of MedicineThe Catholic University of KoreaSeoulRepublic of Korea
  2. 2.Department of Urology, Incheon St. Mary’s Hospital, College of MedicineThe Catholic University of KoreaSeoulRepublic of Korea

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