World Journal of Urology

, Volume 36, Issue 1, pp 79–86 | Cite as

Symptom prevalence, bother, and treatment satisfaction in men with lower urinary tract symptoms in Southeast Asia: a multinational, cross-sectional survey

  • Lap-Yin Ho
  • Peggy Sau-Kwan Chu
  • David Terrence Consigliere
  • Zulkifli Md. Zainuddin
  • David Bolong
  • Chi-Kwok Chan
  • Molly Eng
  • Dac Nhat Huynh
  • Wachira Kochakarn
  • Marie Carmela M. Lapitan
  • Dinh Khanh Le
  • Quang Dung Le
  • Frank Lee
  • Bannakij Lojanapiwat
  • Bao-Ngoc Nguyen
  • Teng-Aik Ong
  • Buenaventura Jose Reyes
  • Apirak Santingamkun
  • Woon-Chau Tsang
  • Paul Abrams
Original Article



The overall objective of the survey was to systematically examine patients’ perspectives on lower urinary tract symptoms (LUTS) and their treatment in Southeast Asia.


A multinational cross-sectional survey involving adult men seeking consultation at urology outpatient clinics because of LUTS in Southeast Asia was conducted using convenience sampling. Self-reported prevalence, bother, treatment and treatment satisfaction of selected LUTS including urgency, nocturia, slow stream, and post-micturition dribble were evaluated.


In total, 1535 eligible patients were enrolled in the survey. A majority of respondents were aged 56–75 years, not employed, and had not undergone prostate operation before. Overall, the self-reported prevalence of nocturia was 88% (95% CI 86–90%), slow stream 61% (95% CI 59–63%), post micturition dribble 55% (95% CI 52–58%), and urgency 52% (95% CI 49–55%). There were marked differences in the country specific prevalence of LUTS complaints. Frequently, symptoms coexisted and were combined with nocturia. More than half of patients felt at least some degree of bother from their symptoms: 61% for urgency, 57% for nocturia, 58% for slow stream, and 60% for post-micturition dribble. Before seeing the present urologists, nearly half of patients have received some form of prescribed treatment and more than 80% of patients indicated they would like to receive treatment.


Men who sought urologist care for LUTS often presented with multiple symptoms. Nocturia emerged as the most common symptom amongst the four core symptoms studied.


Adult Cross-sectional studies Male Prevalence Lower urinary tract symptoms Epidemiology surveys and questionnaires 



Technical support in translation, data collection and analysis was provided by independent translation and research agencies (Elite Asia Interpreters and Ifop-Asia, repsectively) and was funded by Ferring Pharmaceuticals Ltd.

Authors’ contribution

PA and LYH were involved in protocol/project development. All authors were involved in data collection or management. Ifop-Asia was involved in data analysis. All authors were involved in manuscript writing/editing.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Supplementary material

345_2017_2097_MOESM1_ESM.docx (1.4 mb)
Supplementary material 1 (DOCX 820 kb)


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  • Lap-Yin Ho
    • 1
  • Peggy Sau-Kwan Chu
    • 2
  • David Terrence Consigliere
    • 3
  • Zulkifli Md. Zainuddin
    • 4
  • David Bolong
    • 5
  • Chi-Kwok Chan
    • 6
  • Molly Eng
    • 7
  • Dac Nhat Huynh
    • 8
  • Wachira Kochakarn
    • 9
  • Marie Carmela M. Lapitan
    • 10
  • Dinh Khanh Le
    • 11
  • Quang Dung Le
    • 12
  • Frank Lee
    • 13
  • Bannakij Lojanapiwat
    • 14
  • Bao-Ngoc Nguyen
    • 15
  • Teng-Aik Ong
    • 16
  • Buenaventura Jose Reyes
    • 17
  • Apirak Santingamkun
    • 18
  • Woon-Chau Tsang
    • 3
  • Paul Abrams
    • 19
  1. 1.Asia ClinicHong KongChina
  2. 2.Division of Urology, Department of SurgeryTuen Mun HospitalHong KongChina
  3. 3.Department of Urology, University Surgical ClusterNational University HospitalSingaporeSingapore
  4. 4.Urology Unit, Department of SurgeryUniversity Kebangsaan Malaysia Medical CentreKuala LumpurMalaysia
  5. 5.Department of SurgeryUniversity of Santo Tomas HospitalMetro ManilaPhilippines
  6. 6.Division of Urology, Department of Surgery, Prince of Wales HospitalThe Chinese University of Hong KongHong KongChina
  7. 7.Department of SurgeryKhoo Teck Puat HospitalSingaporeSingapore
  8. 8.Department of Urology, University Medical CenterHo Chi Minh City Medicine and Pharmacy UniversityHo Chi MinhVietnam
  9. 9.Division of Urology, Department of SurgeryRamathibodi HospitalBangkokThailand
  10. 10.Division of Urology, Department of SurgeryUniversity of the Philippines - Manila, Philippine General HospitalMetro ManilaPhilippines
  11. 11.Department of Urology, Hue University HospitalHue University of Medicine and PharmacyHueVietnam
  12. 12.Department of SurgeryCan Tho National General HospitalCan ThoVietnam
  13. 13.The Princess Grace HospitalLondonUK
  14. 14.Department of SurgeryChiang Mai UniversityChiang MaiThailand
  15. 15.Bach Mai HospitalHanoiVietnam
  16. 16.Department of Surgery, Faculty of MedicineUniversity of MalayaKuala LumpurMalaysia
  17. 17.St Luke’s Medical CentreManilaPhilippines
  18. 18.Chulalongkorn UniversityBangkokThailand
  19. 19.Bristol Urological InstituteSouthmead HospitalBristolUK

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