Abstract
Purpose
To investigate the efficacy and technical applicability of cavitron ultrasonic surgical aspirator (CUSA)-driven zero-ischemia open partial nephrectomy in patients with renal tumors.
Materials and methods
We prospectively collected data of 13 consecutive patients, who underwent open partial nephrectomy under non-ischemic conditions. Tumor resection was done using an ultrasonic device (CUSA/SONOCA 300). Demographic and laboratory data, tumor characteristics, perioperative, and postoperative variables were evaluated.
Results
The median age was 60.0 years (range 40–76); body mass index 28.0 kg/m2 (range 22.9–43.3); tumor size 37.0 mm (range 11–110 mm). Patient were stratified according to the PADUA score into low- (score 6–7; n − 4), intermediate- (score 8–9; n − 5), and high-risk (score of >10; n − 4) groups, and the median score was 9.0 (range 6–13; SD +2.3). The vast majority of kidney tumors were diagnosed incidentally (n − 11; 84.6 %). Median operative time was 175 min (55–270 min); median time of tumor extirpation was 12 min (6–25 min); and median blood loss was 250 ml. Serum creatinine, glomerular filtration rate, and hemoglobin were nearly unaltered before and after surgery in 11 cases (84.6 %). Three patients received a blood transfusion (Clavien–Dindo Grade II); one had Grade IIIa complication (insertion of double J stent without general anesthesia); and three had Grade IIIb complications (insertion of double J under general anesthesia).
Conclusions
The ultrasonic device demonstrated acceptable hemostatic and resection properties during open partial nephrectomy without ischemia. Our series showed promising perioperative and postoperative outcomes that may help in maximizing preservation of renal function in partial nephrectomy candidates.
Similar content being viewed by others
Abbreviations
- BMI:
-
Body mass index
- CT:
-
Computed tomography
- CUSA:
-
Cavitron ultrasonic surgical aspirator
- EBL:
-
Estimated blood loss
- GFR:
-
Glomerular filtration rate
- MRI:
-
Magnetic resonance imaging
- PN:
-
Partial nephrectomy
References
Thompson RH, Lane BR, Lohse CM, Leibovich BC, Fergany A, Frank I, Gill IS, Blute ML, Campbell SC (2012) Renal function after partial nephrectomy: effect of warm ischemia relative to quantity and quality of preserved kidney. Urology 79(2):356–360
Ficarra V, Novara G, Secco S, Macchi V, Porzionato A, De Caro R, Artibani W (2009) Preoperative aspects and dimensions used for an anatomical (PADUA) classification of renal tumours in patients who are candidates for nephron-sparing surgery. Eur Urol 56(5):786–793
Simone G, Ferriero M, Papalia R, Costantini M, Guaglianone S, Gallucci M (2013) Zero-ischemia minimally invasive partial nephrectomy. Curr Urol Rep 14(5):465–470
Chopp RT, Shah BB, Addonizio JC (1983) Use of ultrasonic surgical aspirator in renal surgery. Urology 22(2):157–159
Flann ES, Ransohoff J, Wunchinich D, Broadwin A (1978) Preliminary experience with ultrasonic aspiration in neurosurgery. Neurosurgery 2:240–245
Addonizio JC, Choudhury MS, Sayegh N, Chopp RT (1984) Cavitron ultrasonic surgical aspirator. Applications in urologic surgery. Urology 23(5):417–420
Muraki J, Addonizio JC, Lastarria E, Eshghi M, Choudhury MS (1993) New Cavitron system (CUSA/CEM): its application for kidney surgery. Urology 41(2):195–198
Melzer RB, Wood TW, Landau ST, Smith JA Jr (1985) Combination of CUSA and neodymium:YAG laser for canine partial nephrectomy. J Urol 134(3):620–622
Belghiti J, Hiramatsu K, Benoist S, Massault P, Sauvanet A, Farges O (1990) Seven hundred forty-seven hepatectomies in the 1990s: an update to evaluate the actual risk of liver resection. J Am Coll Surg 2000(191):38–46
Lochan R, Ansari I, Coates R, Robinson SM, White SA (2013) Methods of haemostasis during liver resection—A UK National Survey. Dig Surg. 30(4–5):375–382
Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213
Russo P, Mano R (2014) Open mini-flank partial nephrectomy: an essential contemporary operation. Korean J Urol 55(9):557–567
Thomas AZ, Smyth L, Hennessey D, O’Kelly F, Moran D, Lynch TH (2013) Zero ischemia laparoscopic partial thulium laser nephrectomy. J Endourol 27(11):1366–1370
Sciarra A, Von Heland M, Minisola F, Salciccia S, Cattarino S, Gentile V (2013) Thulium laser supported nephron sparing surgery for renal cell carcinoma. J Urol 190(2):698–701
Gill IS, Kavoussi LR, Lane BR et al (2007) Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors. J Urol 178:41–46
Fergany AF, Saad IR, Woo L et al (2006) Open partial nephrectomy for tumor in a solitary kidney: experience with 400 cases. J Urol 175:1630–1633
Kopp RP, Mehrazin R, Palazzi K, Bazzi WM, Patterson AL, Derweesh IH (2012) Factors affecting renal function after open partial nephrectomy—a comparison of clampless and clamped warm ischemic technique. Urology 80(4):865–870
Conflict of interest
I hereby certify that the manuscript or portions thereof are not under considerations by another journal or electronic publication and have not been previously published. Authors fully support this statement.
Ethical standard
An ethical approval for the study was obtained under No. 2145/2013 through the Ethic committee of Medical University in Vienna.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Weibl, P., Shariat, S.F. & Klatte, T. Partial nephrectomy driven by cavitron ultrasonic surgical aspirator under zero ischemia: a pilot study. World J Urol 33, 2015–2021 (2015). https://doi.org/10.1007/s00345-015-1569-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00345-015-1569-5