Abstract
Purpose
To estimate the relationship between the history of childhood dysfunctional voiding and urinary incontinence (UI) in adult women with and without clinical UI and to estimate its relationship with stress, urge, and mixed UI.
Materials and methods
Using a case–control study, we surveyed adult women with or without UI using a validated dysfunctional voiding questionnaire. Cases were clinically classified as stress, urge, or mixed UI. Patient characteristics were compared using Student’s t-test, chi-square test, and Fisher’s exact test. Confounders were controlled through logistic regression. We compared the history of childhood dysfunctional voiding status among the three UI subtypes using multinomial logistic regression.
Results
We recruited 267 cases (120 stress, 37 urge, 98 mixed, and 12 other UI) and 107 controls. Mean age of cases and controls were 58 and 52 years and BMI 26 and 23 kg/m², respectively. Fifty-six percent of cases (48% stress, 65% urge, and 62% mixed UI) had a prevalence of childhood dysfunctional voiding compared to controls (40%) (P = 0.06). After adjusting for confounders, women with adult UI had a twofold increased odds (95% CI = 1.2–3.4, P = 0.006) of childhood dysfunctional voiding compared with controls. The highest prevalence of dysfunctional voiding was with urge UI (OR = 4.4, 95% CI = 1.8–10.7) followed by mixed UI (OR = 2.7, 95% CI = 1.5–5.2), and finally stress UI (OR = 1.4, 95% CI = 0.8–2.5).
Conclusion
Childhood dysfunctional voiding may predict adult bladder control problems. This association is strongest in women with urge UI followed by mixed UI, but not different between women with stress UI and controls.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Fowler CJ, Griffiths D, de Groat WC (2008) The neural control of micturition. Nat Rev Neurosci 9:453–466
Holmdahl G, Hanson E, Hanson M, Hellstrom AL, Hjalmas K, Sillen U (1996) Four-hour voiding observation in healthy infants. J Urol 156:1809–1812
Norgaard JP, van Gool JD, Hjalmas K, Djurhuus JC, Hellstrom AL (1998) Standardization and definitions in lower urinary tract dysfunction in children. International children’s continence society. Br J Urol 81:1–16
Krantz I, Jylkas E, Ahlberg BM, Wedel H (1994) On the epidemiology of nocturnal enuresis–a critical review of methods used in descriptive epidemiological studies on nocturnal enuresis. Scand J Urol Nephrol Suppl 163:75–82
Swithinbank LV, Brookes ST, Shepherd AM, Abrams P (1998) The natural history of urinary symptoms during adolescence. Br J Urol 81:90–93
Bloom DA, Seeley WW, Ritchey ML, McGuire EJ (1993) Toilet habits and continence in children: an opportunity sampling in search of normal parameters. J Urol 149:1087–1090
Hellstrom AL, Hanson E, Hansson S, Hjalmas K, Jodal U (1990) Micturition habits and incontinence in 7-year-old Swedish school entrants. Eur J Pediatr 149:434–437
Moore KH, Richmond DH, Parys BT (1991) Sex distribution of adult idiopathic detrusor instability in relation to childhood bedwetting. Br J Urol 68:479–482
Foldspang A, Mommsen S (1994) Adult female urinary incontinence and childhood bedwetting. J Urol 152:85–88
Kuh D, Cardozo L, Hardy R (1999) Urinary incontinence in middle aged women: childhood enuresis and other lifetime risk factors in a British prospective cohort. J Epidemiol Community Health 53:453–458
Fitzgerald MP, Thom DH, Wassel-Fyr C, Subak L, Brubaker L, Van Den Eeden SK, Brown JS (2006) Childhood urinary symptoms predict adult overactive bladder symptoms. J Urol 175:989–993
Minassian VA, Lovatsis D, Pascali D, Alarab M, Drutz HP (2006) Effect of childhood dysfunctional voiding on urinary incontinence in adult women. Obstet Gynecol 107:1247–1251
Farhat W, Bagli DJ, Capolicchio G, O’Reilly S, Merguerian PA, Khoury A, McLorie GA (2000) The dysfunctional voiding scoring system: quantitative standardization of dysfunctional voiding symptoms in children. J Urol 164:1011–1015
Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, Van Kerrebroeck P, Victor A, Wein A (2002) The standardisation of terminology of lower urinary tract function: report from the standardisation sub-committee of the international continence society. Neurourol Urodyn 21:167–178
Duel BP, Steinberg-Epstein R, Hill M, Lerner M (2003) A survey of voiding dysfunction in children with attention deficit-hyperactivity disorder. J Urol 170:1521–1523
Upadhyay J, Bolduc S, Bagli DJ, McLorie GA, Khoury AE, Farhat W (2003) Use of the dysfunctional voiding symptom score to predict resolution of vesicoureteral reflux in children with voiding dysfunction. J Urol 169:5
Elia G, Bergman J, Dye TD (2002) Familial incidence of urinary incontinence. Am J Obstet Gynecol 187:53–55
Buchsbaum GM, Duecy EE (2008) Incontinence and pelvic organ prolapse in parous/nulliparous pairs of identical twins. Neurourol Urodyn 27:496–498
Hannestad YS, Lie RT, Rortveit G, Hunskaar S (2004) Familial risk of urinary incontinence in women: population based cross sectional study. BMJ 329:889–891
Rohr G, Kragstrup J, Gaist D, Christensen K (2004) Genetic and environmental influences on urinary incontinence: a Danish population-based twin study of middle-aged and elderly women. Acta Obstet Gynecol Scand 83:978–982
Cheung W, Bluth MJ, Johns C, Khan S, Lin YY, Bluth MH (2010) Peripheral blood mononuclear cell gene array profiles in patients with overactive bladder. Urology 75:896–901
Davila GW, Bernier F, Franco J, Kopka SL (2003) Bladder dysfunction in sexual abuse survivors. J Urol 170:476–479
Conflict of interest
The authors have no disclosures.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Minassian, V.A., Langroudi, M.H., Parekh, M. et al. Childhood dysfunctional voiding is differentially associated with urinary incontinence subtypes in women. World J Urol 30, 111–115 (2012). https://doi.org/10.1007/s00345-011-0665-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00345-011-0665-4