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Acid-base and electrolyte disorders after urinary diversion

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Abstract

The use of bowel in urologic reconstructive procedures may result in numerous short and long-term complications, including well-described acid-base and electrolyte disorders. Many of these metabolic alterations are influenced by how solute absorption occurs across the particular bowel segment chosen for reconstruction. Solute absorption is impacted by: (1) the segment of bowel used, (2) the surface area of bowel used, (3) the time of retention of urine, (4) the concentration of solutes in the urine, (5) renal function, and (6) the pH and osmolality of the urine. These factors affect the type and amount of solutes absorbed, as well as the severity of metabolic complications that develop.

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References

  1. Boyd JD (1931) Chronic acidosis secondary to ureteral transplantation. Am J Dis Child 42:366–371

    Google Scholar 

  2. Boyd SD, Schiff WM, Skinner DG, Lieskovsky G, Kanellos AW, Klimaszewski AD (1989) Prospective study of metabolic abnormalities in patients with continent Kock pouch urinary diversion. Urology 33:85–88

    Article  CAS  PubMed  Google Scholar 

  3. Castro JE, Ram MD (1970) Electrolyte imbalance following ileal urinary diversion. Br J Urol 42:29–32

    CAS  PubMed  Google Scholar 

  4. Edwards DH (1984) Hyperammonemic encephalopathy related to ureterosigmoidostomy. Arch Neurol 41:1211–1212

    CAS  PubMed  Google Scholar 

  5. Gafter U, Kraut JA, Lee DB, Silis V, Walling MW, Kurokawa K, Haussler MR, Coburn JW (1980) Effect of metabolic acidosis on intestinal absorption of calcium and phosphorus. Am J Physiol 239:G480–484

    CAS  PubMed  Google Scholar 

  6. Golimbu M, Morales P (1973) Electrolyte disturbances in jejunal urinary diversion. Urology 1:432–438

    Article  CAS  PubMed  Google Scholar 

  7. Golimbu M, Morales P (1975) Jejunal conduits: technique and complications. J Urol 113:787–795

    CAS  PubMed  Google Scholar 

  8. Gosalbez RJr, Woodard JR, Broecker BH, Warshaw B (1993) Metabolic complications of the use of stomach for urinary reconstruction. J Urol 150:710–712

    PubMed  Google Scholar 

  9. Kaveggia FF, Thompson JS, Schafer EC, Fischer JL, Taylor RJ (1990) Hyperammonemic encephalopathy in urinary diversion with urea-splitting urinary tract infection. Arch Int Med 150:2389–2392

    Article  CAS  Google Scholar 

  10. Klein EA, Montie JE, Montague DK, Kay R, Straffon RA (1986) Jejunal conduit urinary diversion. J Urol 135:244–246

    CAS  PubMed  Google Scholar 

  11. Koch MO, McDougal WS (1985) The pathophysiology of hypercholoremic metabolic acidosis after urinary diversion through intestinal segments. Surgery 98:561–570

    CAS  PubMed  Google Scholar 

  12. Koch MO, McDougal WS (1985) Chlorpromazine: adjuvant therapy for the metabolic derangements created by urinary diversion through intestinal segments. J Urol 134:165–169

    CAS  PubMed  Google Scholar 

  13. Koch MO, McDougal WS (1985) Nicotinic acid: treatment for the hyperchloremic acidosis following urinary diversion through intestinal segments. J Urol 134:162–164

    CAS  PubMed  Google Scholar 

  14. Koch MO, Gurevitch E, Hill DE, McDougal WS (1990) Urinary solute transport by intestinal segments: a comparative study of ileum and colon in rats. J Urol 143:1275–1279

    CAS  PubMed  Google Scholar 

  15. Koff SA (1975) Mechanism of electrolyte imbalance following urointestinal anastomoses. Urology 5:109–114

    Article  CAS  PubMed  Google Scholar 

  16. Lemann JJr, Litzow JR, Lennon EJ (1966) The effects of chronic acid loads in normal man: further evidence for participation of bone mineral in the defense against chronic metabolic acidosis. J Clin Invest 45:1608–1614

    CAS  PubMed  Google Scholar 

  17. Lemann JJr, Litzow JR, Lennon EJ (1967) Studies of the mechanism by which chronic metabolic acidosis augments urinary calcium excretion in man. J Clin Invest 46:1318–1328

    CAS  Google Scholar 

  18. McDermott WVJr (1957) Diversion of urine to the intestines as a factor in ammoniagenic coma. N Engl J Med 256:460

    PubMed  Google Scholar 

  19. McDougal WS, Heimburger S, Wilmore DW, Pruitt BAJr (1978) The effect of exogenous substrate on hepatic metabolism and membrane transport during endotoxemia. Surgery 83:55–61

    Google Scholar 

  20. McDougal WS (1992) Metabolic complications of urinary intestinal diversion. J Urol 147:1199–1208

    CAS  PubMed  Google Scholar 

  21. McDougal WS, Stampfer DS, Kirley S, Bennett PM, Lin CW (1995) Intestinal ammonium transport by ammonium and hydrogen exchange. J Am Coll Surg 181:241–248

    CAS  PubMed  Google Scholar 

  22. Mills RD, Studer UE (1999) Metabolic consequences of continent urinary diver-sion. J Urol 161:1057–1066

    Article  CAS  PubMed  Google Scholar 

  23. Nguyen DH, Bain MA, Salmonson KL, Ganesan GS, Burns MW, Mitchell ME (1993) The syndrome of dysuria and hematuria in pediatric urinary reconstruction with stomach. J Urol 150:707–709

    CAS  PubMed  Google Scholar 

  24. Plawker MW, Rabinowitz SS, Etwaru DJ, Glassberg KI (1995) Hypergastrinemia, dysuria-hematuria and metabolic alkalosis: complications associated with gastrocystoplasty. J Urol 154:546–549

    CAS  PubMed  Google Scholar 

  25. Silberman R (1958), Ammonia intoxication following ureterosigmoidostomy in a patient with liver disease. Lancet 2:937

    Article  CAS  PubMed  Google Scholar 

  26. Stampfer DS, McDougal WS (1997), Inhibition of the sodium/hydrogen antiport by ammonium ion. J Urol 157:362–365

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Cigdem Tanrikut.

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Tanrikut, C., McDougal, W.S. Acid-base and electrolyte disorders after urinary diversion. World J Urol 22, 168–171 (2004). https://doi.org/10.1007/s00345-004-0430-z

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  • DOI: https://doi.org/10.1007/s00345-004-0430-z

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