World Journal of Urology

, Volume 21, Issue 5, pp 356–363 | Cite as

G. Frank Lydston (1858–1923) revisited: androgen therapy by testicular implantation in the early twentieth century

  • Dirk Schultheiss
  • Rainer M. Engel
Historical Vignette


At the beginning of the twentieth century the transplantation or implantation of either human or animal testicular tissue was an appealing form of androgen therapy in hypogonadal and aging males. This article on the history of medicine discusses the work of the American urologist G. Frank Lydston from Chicago, who was a well-known and respected surgeon in the academic world and was involved in the early clinical trials of this procedure.


Androgens Aging male Erectile dysfunction Urology Andrology Transplantation Testis History of medicine 


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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  1. 1.Department of Urology and Pediatric UrologyHannover Medical SchoolHannoverGermany
  2. 2.William P. Didusch MuseumAmerican Urological AssociationBaltimoreUSA

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