Abstract.
The aim of our studies was to develop a method to determine the absorption coefficient of a turbid medium in a reflection geometry with small source–detector separations. Therefore, the time-integrated microscopic Beer–Lambert law (MBL) was modified in order to obtain the absolute absorption coefficient from mean time of flight and dc-intensity measurements. The new technique was evaluated using turbid phantoms having varying scattering (μs ′ between 0.2 and 2.2 mm-1) and absorbing properties (μa between 0.04 and 0.14 mm-1), comparable to many biological tissues at various source–detector separations between 3 and 11 mm. The measurements were performed at a wavelength of 1064 nm. We found that this new method was able to determine the absolute absorption coefficient of the selected phantoms with a standard error of less than 0.005 mm-1 over the range of optical properties investigated.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 23 November 2001 / Revised version: 28 February 2002 / Published online: 14 May 2002
Rights and permissions
About this article
Cite this article
Willmann, S., Terenji, A., Osterholz, J. et al. Absolute absorber quantification in turbid media at small source–detector separations. Appl Phys B 74, 589–595 (2002). https://doi.org/10.1007/s003400200853
Published:
Issue Date:
DOI: https://doi.org/10.1007/s003400200853