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Biosynthesis of carbon quantum dot nanocomposite as an advanced material for simultaneous electrochemical sensing of D-glucose and paracetamol

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Abstract

Biosynthesis of carbon-based materials via pyrolysis and hydrothermal methods have emerged as a cost-effective strategy towards fabrication of biosensors for electrochemical sensing applications. The porosity, surface area and active sites on bio-derived carbon materials greatly influence the electrochemical sensing performance of modified electrodes. Herein, we report synthesis of carbon quantum dots by pyrolysis of Halimeda Opuntia green algae and doping with silver nanoparticles (AgNPs@CQDs) for the fabrication of electrochemical sensing platform of D-glucose and paracetamol. The structural and morphological features of AgNPs@CQDs were analyzed using SEM, XRD, FTIR and UV–Vis spectroscopy. Simultaneous determination of D-glucose and paracetamol in 1M KOH solution was performed using GCE-modified AgNPs@CQDs. The cyclic voltammetry confirms excellent electrochemical performance of GCE-modified AgNPs@CQDs electrodes. AgNPs@CQDs composites electrodes show improved sensing response in the pH range 4–7 with optimum values at pH = 7 for both D-glucose and paracetamol. The GCE modified by AgNPs@CQDs electrodes exhibit highly linear response for both D-glucose and paracetamol. Limit of detection was found to be 0.32 µM and 0.29 µM for D-glucose and paracetamol, respectively. The GCE-modified AgNPs@CQDs composites electrodes show fast response time of 33 s and 21 s, respectively, for D-glucose and paracetamol at a concentration of 10 µM. Furthermore, the AgNPs@CQDs composites electrodes show highly selective response towards D-glucose and paracetamol against various other target analytes. Due to ease of bio synthesis, low-cost fabrication, excellent electrochemical performance towards detection of D-glucose and paracetamol, the AgNPs@CQDs could be a potential material to fabricate versatile sensors towards simultaneous determination of D-glucose and paracetamol.

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Acknowledgements

The authors would like to acknowledge financial support for this work, from the Deanship of Scientific research (DSR), University of Tabuk, Tabuk, Saudi Arabia, under Grant No. S-1443-0020.

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Authors and Affiliations

  1. Department of Physics, Faculty of Science, University of Tabuk, 71491, Tabuk, Saudi Arabia

    Syed Khasim, S. A. Al-Ghamdi, A. A. A. Darwish & Taymour A. Hamdalla

  2. Department of Physics, Faculty of Education at Al-Mahweet, Sana’s University, Al-Mahweet, Yemen

    A. A. A. Darwish

  3. Department of Physics, Faculty of Science, Alexandria University, Alexandria, Egypt

    Taymour A. Hamdalla

  4. Department of Physics, Ghousia College of Engineering, Ramanagaram, Karnataka, 562159, India

    Apsar Pasha

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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by SK, SAA-G, AD and AP. The first draft of the manuscript was written by SAA-G, SK and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Khasim, S., Al-Ghamdi, S.A., Darwish, A.A.A. et al. Biosynthesis of carbon quantum dot nanocomposite as an advanced material for simultaneous electrochemical sensing of D-glucose and paracetamol. Appl. Phys. A 129, 800 (2023). https://doi.org/10.1007/s00339-023-07073-3

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