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Ultra-sensitive smartphone assisted-colorimetric and non-enzymatic electrochemical sensor behaviors of zinc doped MnO2 nanocomposite: a comparative study on highly selective sensor design against dopamine, ascorbic acid, gallic acid, and tannic acid

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Abstract

Although evolving technology enables the production of sensors with excellent properties, the development of a fast-response, portable, and low-cost sensor is very important for food detection and also for disease diagnosis. Herein, zinc doped manganese oxide nanocomposites (Zn:MnO2 NCs) were designed as smartphone-integrated colorimetric and non-enzymatic electrochemical sensors with high sensitivity and selectivity. According to the Transmission electron microscopy (TEM) results showed that the Zn:MnO2 NCs had a spherical shape with a uniform particle size of less than 10 nm. As one of the most important results, the colorimetric sensing behavior of the Zn:MnO2 NCs was showed excellent fast and selective sensitivity against dopamine, ascorbic acid, gallic acid, and tannic acid among the various bio-analytes such as sugars, amino acids, hormones, and phenolic compounds. The Zn:MnO2 NCs were successfully used as smartphone supported paper based sensor against dopamine, gallic acid, and tannic acid using RGB analysis and with low limit of detection (LOD) values of 2.89, 3.88, and 7.81 μM, respectively. Moreover, Zn:MnO2 exhibited excellent a non-enzymatic electrochemical sensor performance against ascorbic acid with a low LOD of 239 nM and high sensitivity of 44.73 μA/cm2 mM in a concentration range of 0.52–11.35 mM. These findings emphasize that the designed Zn:MnO2 NCs based sensors has a potential as easily applicable and rapid sensor systems against of ascorbic acid, gallic acid, tannic acid and dopamine for real food and blood samples that as a point-of-care detection systems.

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Acknowledgements

This work was supported by Scientific Research Projects Coordination Unit of Istanbul University-Cerrahpasa. Project number: 32438.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Engineering, Istanbul University-Cerrahpasa, Avcılar, 34320, Istanbul, Turkey

    Ezgi Tan & Selcan Karakuş

  2. Department of Electrical and Electronics Eng., Maltepe University, Istanbul, Turkey

    Gülsen Baytemir & Nevin Taşaltın

  3. Department of Basic Sciences, Maltepe University, Istanbul, Turkey

    Nevin Taşaltın

  4. Dept. of Renewable Energy Tech. and Management, Maltepe University, Istanbul, Turkey

    Nevin Taşaltın

  5. Maltepe University Environment and Energy Technologies Research Center, Istanbul, Turkey

    Nevin Taşaltın

  6. CONSENS Inc., Maltepe University Research Center, Technopark Istanbul, Istanbul, Turkey

    Nevin Taşaltın

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  1. Ezgi Tan
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Tan, E., Baytemir, G., Taşaltın, N. et al. Ultra-sensitive smartphone assisted-colorimetric and non-enzymatic electrochemical sensor behaviors of zinc doped MnO2 nanocomposite: a comparative study on highly selective sensor design against dopamine, ascorbic acid, gallic acid, and tannic acid. Appl. Phys. A 129, 214 (2023). https://doi.org/10.1007/s00339-023-06497-1

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