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Green synthesis of carbon nanodots for direct and rapid determination of theophylline through fluorescence turn on–off strategy

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Abstract

Main conclusion

Carbon dots (CDs) have attracted more and more attention due to their low toxicity, good biocompatibility and easy preparation. However, synthesis of CDs with high quantum yield using green and economic method is still challenging. Herein, an effective synthesis route was reported for green synthesizing CDs using waste chicken eggshell membrane as carbon source via microwave-assisted method. The obtained CDs showed good photo-stability with a high quantum yield of 19.5%. The as-prepared CDs was designed as a fluorescent probe for facile, rapid, sensitive determination of theophylline (TP) based on the fluorescence turn on–off strategy. The designed method exhibited good performance for the determination of TP. Under the optimal conditions, the fluorescent response of CDs was proportional to the TP concentrations in the range of 0.1–1 and 1–1000 μM with limit of detection of 28 nM. Moreover, the proposed method was applied to detect the TP content in tea samples. The as-prepared CDs provide a green and economic approach for the food safety test.

Graphical abstract

Eggshell membrane-derived carbon nanodots for direct and rapid detection of theophylline.

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Acknowledgements

This work was sponsored by the key Scientific Research Projects in University of Henan Province (21A150050), 1000 Talents Program of Zhongyuan (ZYQR201912153), Plan for Young Excellent Teachers in Universities of Henan Province (No. 2017GGJS100), Nanhu Scholars Program for Young Scholars of XYNU.

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Xinyang Key Laboratory of Functional Nanomaterials for Bioanalysis, Institute for Conservation and Utilization of Agro-Bioresources in Dabie Mountains, Xinyang Normal University, Xinyang, 464000, People’s Republic of China

    Hongding Zhang, Sifei Wu, Man Gao, Mengwei Sun, Jiaoyu Wang & Hai-Bo Wang

  2. Xinyang Branch, Henan Province Institute of Boiler and Pressure Vessel Safety Testing, Xinyang, 464000, People’s Republic of China

    Zhenhua Xing

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  1. Hongding Zhang
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  2. Sifei Wu
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Zhang, H., Wu, S., Xing, Z. et al. Green synthesis of carbon nanodots for direct and rapid determination of theophylline through fluorescence turn on–off strategy. Appl. Phys. A 128, 356 (2022). https://doi.org/10.1007/s00339-022-05485-1

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