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Applied Physics A

, 124:394 | Cite as

Detection of DNA hybridization using graphene-coated black phosphorus surface plasmon resonance sensor

  • Sarika Pal
  • Alka Verma
  • S. Raikwar
  • Y. K. Prajapati
  • J. P. Saini
Rapid communication

Abstract

In this paper, graphene-coated black phosphorus at the metal surface for the detection of DNA hybridization event is numerically demonstrated. The strategy consists of placing the sensing medium on top of black phosphorus–graphene-coated SPR which interfaces with phosphate-buffered saline solution carrying single-stranded DNA. Upon hybridization with its complementary DNA, desorption of the nanostructures takes place and thus enables the sensitive detection of the DNA hybridization event. The proposed sensor exhibits a sensitivity (125 ο/RIU), detection accuracy (0.95) and quality factor (13.62 RIU−1) for complementary DNA. In comparison with other reported papers, our suggested sensor provides much better performance. Thus, this label-free DNA detection platform should spur off new interest towards the use of black phosphorus–graphene-coated SPR interfaces.

Abbreviations

A

Adenine

ATR

Attenuated total reflection

BP

Black phosphorus

C

Cytocine

ca

Concentration of adsorbed molecule

DNA

Deoxyribonucleic acid

DA

Detection accuracy

dsDNA

Double-stranded DNA

FWHM

Full width at half maximum

Au

Gold

G

Guanine

MoS2

Molybdenum disulfide

MoSe2

Molybdenum diselenide

nM

Nanomolar

λ

Operating wavelength

PBS

Phosphate-buffered saline

Q.F

Quality factor

R

Reflectance

RI

Refractive index

RIU

Refractive index unit

nS

RI of sensing medium before hybridization

nH

RI of sensing medium after DNA hybridization

Adsorbate

RI change due to DNA

S

Sensitivity

ssDNA

Single-stranded DNA

SPR

Surface plasmon resonance

SPW

Surface plasmon wave

TMDC

Transition metal dichalcogenides

T

Thymine

TM

Transverse magnetic

WS2

Tungsten disulfide

WSe2

Tungsten diselenide

kspw

Wave vector of evanescent wave

kev

Wave vector of surface plasmon wave

Notes

Acknowledgements

This work is partially supported under Project no. 34/14/10/2017-BRNS/34285 by Board of Research in Nuclear Sciences (BRNS), Department of Atomic Energy (DAE), Government of India.

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Sarika Pal
    • 1
  • Alka Verma
    • 2
  • S. Raikwar
    • 3
  • Y. K. Prajapati
    • 4
  • J. P. Saini
    • 5
  1. 1.Department of Electronics and Communication EngineeringK.I.E.T Group of InstitutionsGhaziabadIndia
  2. 2.Department of Electronics EngineeringInstitute of Engineering and Rural TechnologyAllahabadIndia
  3. 3.Department of Electronics and Communication EngineeringBuldelkhand Institute of Engineering and TechnologyJhansiIndia
  4. 4.Department of Electronics and Communication EngineeringMotilal Nehru National Institute of TechnologyAllahabadIndia
  5. 5.Department of Electronics and Communication EngineeringNetaji Subhas Institute of Technology (NSIT)New DelhiIndia

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