Applied Physics A

, 124:283 | Cite as

Influence of polymerization conditions on the refractive index of poly(ethylene glycol) diacrylate (PEGDA) hydrogels

  • Zhi Feng Zhang
  • Xinxian Ma
  • Haibin Wang
  • Fei Ye


This paper studies the influences of fabrication parameters on the optical properties of poly(ethylene glycol) diacrylate(PEGDA) hydrogels during polymerization, including the irradiation intensity, irradiation time, photoinitiator concentration, and water content. The refractive index of PEGDA hydrogels polymerized under various conditions is measured, with the results shown to be valuable for future research applying PEGDA hydrogels as optical materials. In addition, it is found that the photoinitiator concentration used can be as low as 1.0 wt%, which is severalfold lower than that previously reported, making PEGDA hydrogels more desirable for bioapplications.



This work was supported by Ningxia Education Department under Grant no. NGY2016198, and by the College of Chemistry and Chemical Engineering, Ningxia Normal University under Grant no. HGZD16-05.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no competing financial interests


  1. 1.
    J.L. Drury, D.J. Mooney, Biomaterials 24, 4337 (2003)CrossRefGoogle Scholar
  2. 2.
    M.R. Hynd, J.N. Turner, W. Shain, J. Biomater. Sci. Polym. Ed. 18, 1223 (2007)CrossRefGoogle Scholar
  3. 3.
    Y. Luo, M.S. Shoichet, Nat. Mater. 3, 249 (2004)ADSCrossRefGoogle Scholar
  4. 4.
    J. Thiele, Y. Ma, S.M.C. Bruekers, S. Ma, W.T.S. Huck, Adv. Mater. 26, 125 (2014)CrossRefGoogle Scholar
  5. 5.
    A. Guiseppi-Elie, Biomaterials 31, 2701 (2010)CrossRefGoogle Scholar
  6. 6.
    Z. Liu, P. Calvert, Adv. Mater. 12, 288 (2000)ADSCrossRefGoogle Scholar
  7. 7.
    M.B. Applegate, G. Perotto, D.L. Kaplan, F.G. Omenetto, Biomed. Opt. Express 6, 4221 (2015)CrossRefGoogle Scholar
  8. 8.
    M. Choi, J.W. Choi, S. Kim, S. Nizamoglu, S.K. Hahn, S.H. Yun, Nat. Photonics 7, 987 (2013)ADSCrossRefGoogle Scholar
  9. 9.
    M. Choi, M. Humar, S. Kim, S.-H. Yun, Adv. Mater. 27, 4081 (2015)CrossRefGoogle Scholar
  10. 10.
    A. Jain, A.H. Yang, D. Erickson, Opt. Lett. 37, 1472 (2012)ADSCrossRefGoogle Scholar
  11. 11.
    F.J. Arregui, Z. Ciaurriz, M. Oneca, I.R. Matías, Sens. Actuators B Chem. 96, 165 (2003)CrossRefGoogle Scholar
  12. 12.
    R.A. Barry, P. Wiltzius, Langmuir 22, 1369 (2006)CrossRefGoogle Scholar
  13. 13.
    T. Forster, C. Strohhofer, K. Bock, P. Kasak, M. Danko, Z. Kronekova, T. Nedelcev, I. Krupa, I. Lacik, Solid-State Sens. Actuators Microsyst. Conf. 2009 TRANSDUCERS 2009 Int. IEEE, 2009), pp. 1218–1221Google Scholar
  14. 14.
    Y. Wang, C.-J. Huang, U. Jonas, T. Wei, J. Dostalek, W. Knoll, Biosens. Bioelectron. 25, 1663 (2010)CrossRefGoogle Scholar
  15. 15.
    Q. Zhang, Y. Wang, A. Mateescu, K. Sergelen, A. Kibrom, U. Jonas, T. Wei, J. Dostalek, Talanta 104, 149 (2013)CrossRefGoogle Scholar
  16. 16.
    W. Li, J. Wang, J. Ren, X. Qu, Adv. Mater. 25, 6737 (2013)CrossRefGoogle Scholar
  17. 17.
    S. Nizamoglu, M.C. Gather, M. Humar, M. Choi, S. Kim, K.S. Kim, S.K. Hahn, G. Scarcelli, M. Randolph, R.W. Redmond, S.H. Yun, Nat. Commun. 7, 10374 (2016)ADSCrossRefGoogle Scholar
  18. 18.
    S. Lee, X. Tong, F. Yang, Acta Biomater. 10, 4167 (2014)CrossRefGoogle Scholar
  19. 19.
    N.A. Stocke, X. Zhang, J.Z. Hilt, J.E. DeRouchey, Macromol. Chem. Phys. 218, 1600340 (2017)CrossRefGoogle Scholar
  20. 20.
    D. Margerison, D.R. Bain, B. Kiely, Polymer 14, 133 (1973)CrossRefGoogle Scholar
  21. 21.
    C.A. Durst, M.P. Cuchiara, E.G. Mansfield, J.L. West, K.J. Grande-Allen, Acta Biomater. 7, 2467 (2011)CrossRefGoogle Scholar
  22. 22.
    A. Cavallo, M. Madaghiele, U. Masullo, M.G. Lionetto, A. Sannino, J. Appl. Polym. Sci. 134, (2017)Google Scholar
  23. 23.
    B. Amsden, Macromolecules 31, 8382 (1998)ADSCrossRefGoogle Scholar
  24. 24.
    F. Ganji, S. Vasheghani-Farahani, E. Vasheghani-Farahani, Iran. Polym. J. 19, 375 (2010)Google Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.College of Chemistry and Chemical EngineeringNingxia Normal UniversityGuyuanChina

Personalised recommendations