Applied Physics A

, 122:184 | Cite as

Femtosecond laser-induced periodic nanostructure creation on PET surface for controlling of cell spreading

  • Yuji Sato
  • Masahiro Tsukamoto
  • Togo Shinonaga
  • Takuya Kawa
Invited Paper
Part of the following topical collections:
  1. Emerging trends in photo-excitations and promising new laser ablation technologies


A new method of periodic nanostructure formation on a polyethylene terephthalate (PET) surface has been developed, employing a femtosecond laser with a wavelength of 1045 nm. To generate structured films, the PET was placed in contact with a silicon (Si) wafer, followed by irradiation with the laser focused on the Si wafer, passing through the PET film. In order to evaluate the surface morphology, atomic force microscopy analysis was conducted on both treated and untreated PET surfaces. From the results, nanostructures with a period of 600 nm and height of 100 nm were formed on the PET film surface by laser treatment. A cell cultivation test was carried out on PET films with and without periodic nanostructures, showing that for nanostructured films, the cells (MG-63) were spread along the periodic grooves; in contrast, random cell spreading was observed for cultures grown on the untreated PET film.


PLLA Silicon Wafer Femtosecond Laser Cell Spreading Laser Fluence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Yuji Sato
    • 1
  • Masahiro Tsukamoto
    • 1
  • Togo Shinonaga
    • 2
  • Takuya Kawa
    • 3
  1. 1.Joining and Welding Research InstituteOsaka UniversityIbarakiJapan
  2. 2.Graduate School of Natural Science and TechnologyOkayama UniversityOkayama-shiJapan
  3. 3.Graduate School of EngineeringOsaka UniversitySuitaJapan

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