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Investigation of pseudo boehmite nanoparticles as an antibacterial agent

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Abstract

Pseudo boehmite nanoparticles were synthesized by using bovine serum albumin as the structure-directing agent. The morphology and crystal phase of the pseudo boehmite nanoparticles were determined by transmission electron microscopy, X-ray diffractograms and Fourier transform infrared spectroscopy. The antibacterial behaviors of pseudo boehmite nanoparticles were investigated using Escherichia coli (gram-negative) and Staphylococcus aureus (gram-positive) as model organisms. The results indicated that the synthesized pseudo boehmite nanoparticles showed high antibacterial activity when compared to plain aluminum oxide, which was assessed by measuring the growth inhibition and testing the zone of inhibition. The plausible mechanism of antibacterial behavior was attributed to the generation of reactive oxygen species by pseudo boehmite nanoparticles.

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Acknowledgments

The authors acknowledge the financial supports from National Natural Science Foundation of China (No. 31201036), Excellent Young Scientist Training Fundation of Guangdong Province in 2014 (No. 4CX14068G) and Science & Technology Fund of Department of Education of Guangdong Province (2012LYM_0069).

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  1. School of Pharmacy, Guangdong Medical College, Dongguan, 523808, People’s Republic of China

    Zhi Chen, Dudu Wu & Jiaxi Chen

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  1. Zhi Chen
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  2. Dudu Wu
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Correspondence to Zhi Chen.

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Chen, Z., Wu, D. & Chen, J. Investigation of pseudo boehmite nanoparticles as an antibacterial agent. Appl. Phys. A 119, 1515–1522 (2015). https://doi.org/10.1007/s00339-015-9129-9

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