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Fabrication of size-controlled three-dimensional structures consisting of electrohydrodynamically produced polycaprolactone micro/nanofibers

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Abstract

In this paper, we report a facile method of fabricating size-controlled three-dimensional (3D) polycaprolactone (PCL) micro/nanofiber structure using a modified electrospinning supplemented with a specially designed solvent bath in which the flow rate of the solvent (EtOH) was controlled. By varying the flow rate of the EtOH into the grounded bath and the electrospinning parameters including a distance between the nozzle and target, the height, diameter, porosity, and micro/nanofiber size of the 3D structures were controlled. To show stable micro/nanofibrous structures under the fabricating conditions, we characterized a process diagram for various flow rates of EtOH and weight percents of PCL. We believe that this modified electrospinning process may be a new means of fabricating micro/nanofibrous 3D structures.

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References

  1. J. Doshi, D.H. Reneker, J. Electrost. 35, 151 (1995)

    Article  Google Scholar 

  2. C.S. Reddy, A. Arinstein, R. Avrahami, E. Zussman, J. Mater. Chem. 19, 7198 (2009)

    Article  Google Scholar 

  3. W.E. Teo, S. Ramakrishna, Compos. Sci. Technol. 69, 1804 (2009)

    Article  Google Scholar 

  4. P.K. Baumgarten, J. Colloid Interface Sci. 36, 71 (1971)

    Article  Google Scholar 

  5. J.H. Yu, S.V. Fridrikh, G.C. Rutledge, Adv. Mater. 16, 1562 (2004)

    Article  Google Scholar 

  6. Y. Yokoyama, S. Hattori, C. Yoshikawa, Y. Yasuda, H. Koyama, T. Takato, H. Kobayashi, Mater. Lett. 63, 754 (2009)

    Article  Google Scholar 

  7. J.K. Hong, S.V. Madihally, Acta Biomat. 6, 4734 (2010)

    Article  Google Scholar 

  8. C.J. Luo, M. Nangrejo, M. Edirisinghe, Polymer 51, 1654 (2010)

    Article  Google Scholar 

  9. Z. Ahmad, M. Rasekh, M. Edirisinghe, Macromol. Mater. Eng. 295, 315–319 (2010)

    Article  Google Scholar 

  10. Z.W. Ma, M. Kotaki, R. Inai, S. Ramakrishna, Tissue Eng. 11, 101 (2005)

    Article  Google Scholar 

  11. M. Shin, H. Yoshimoto, J.P. Vacanti, Tissue Eng. 10, 33 (2004)

    Article  Google Scholar 

  12. T. Sun, S. Mai, D. Norton, J.W. Haycock, A.J. Ryan, S. Macneil, Tissue Eng. 11, 1023 (2005)

    Article  Google Scholar 

  13. A. Subramanian, D. Vu, G.F. Larsen, H.-Y. Lin, J. Biomater. Sci., Polym. Ed. 16, 861 (2005)

    Article  Google Scholar 

  14. A. Thorvaldsson, H. Stenhamre, P. Gatenholm, P. Walkenström, Biomacromolecules 9, 1044 (2008)

    Article  Google Scholar 

  15. Y.M. Ju, J.S. Choi, A. Atala, J.J. Yoo, S.J. Lee, Biomaterials 31, 4313 (2010)

    Article  Google Scholar 

  16. J. Xie, M.R. MacEwan, A.G. Schwartz, Y. Xia, Nanoscale 2, 35 (2010)

    Article  ADS  Google Scholar 

  17. S.J. Kim, D.H. Jang, W.H. Park, B.-M. Min, Polymer 51, 1320 (2010)

    Article  Google Scholar 

  18. T.J. Sill, H.A. von Recum, Biomaterials 29, 1989 (2008)

    Article  Google Scholar 

  19. J.-F. Zhang, D.-Z. Yang, J. Nie, Polym. Adv. Technol. 19, 1150 (2008)

    Article  Google Scholar 

  20. J.K. Hong, S.V. Madihally, Acta Biomat. 6, 4734 (2010)

    Article  Google Scholar 

  21. M.R. Badrossamay, H.A. McIlwee, J.A. Goss, K.K. Parker, Nano Lett. 10, 2257 (2010)

    Article  ADS  Google Scholar 

  22. R. Tzezana, E. Zussman, S. Levenberg, Tissue Eng. Part C Methods 14, 281 (2008)

    Article  Google Scholar 

  23. S. Igarashi, J. Tanaka, H. Kobayashi, J. Nanosci. Nanotechnol. 7, 814 (2007)

    Article  Google Scholar 

  24. S. Yan, L. Xiaoqiang, T. Lianjiang, H. Chen, M. Xiumei, Polymer 50, 4212 (2009)

    Article  Google Scholar 

  25. A.J. Hines, R.N. Maddox, Mass Transfer: Fundamental and Applications (Prentice Hall International, Englewood Cliffs, 1985)

    Google Scholar 

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Correspondence to GeunHyung Kim.

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Hong, S., Kim, G. Fabrication of size-controlled three-dimensional structures consisting of electrohydrodynamically produced polycaprolactone micro/nanofibers. Appl. Phys. A 103, 1009–1014 (2011). https://doi.org/10.1007/s00339-011-6381-5

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  • DOI: https://doi.org/10.1007/s00339-011-6381-5

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