Abstract
In this paper, we report a facile method of fabricating size-controlled three-dimensional (3D) polycaprolactone (PCL) micro/nanofiber structure using a modified electrospinning supplemented with a specially designed solvent bath in which the flow rate of the solvent (EtOH) was controlled. By varying the flow rate of the EtOH into the grounded bath and the electrospinning parameters including a distance between the nozzle and target, the height, diameter, porosity, and micro/nanofiber size of the 3D structures were controlled. To show stable micro/nanofibrous structures under the fabricating conditions, we characterized a process diagram for various flow rates of EtOH and weight percents of PCL. We believe that this modified electrospinning process may be a new means of fabricating micro/nanofibrous 3D structures.
Similar content being viewed by others
References
J. Doshi, D.H. Reneker, J. Electrost. 35, 151 (1995)
C.S. Reddy, A. Arinstein, R. Avrahami, E. Zussman, J. Mater. Chem. 19, 7198 (2009)
W.E. Teo, S. Ramakrishna, Compos. Sci. Technol. 69, 1804 (2009)
P.K. Baumgarten, J. Colloid Interface Sci. 36, 71 (1971)
J.H. Yu, S.V. Fridrikh, G.C. Rutledge, Adv. Mater. 16, 1562 (2004)
Y. Yokoyama, S. Hattori, C. Yoshikawa, Y. Yasuda, H. Koyama, T. Takato, H. Kobayashi, Mater. Lett. 63, 754 (2009)
J.K. Hong, S.V. Madihally, Acta Biomat. 6, 4734 (2010)
C.J. Luo, M. Nangrejo, M. Edirisinghe, Polymer 51, 1654 (2010)
Z. Ahmad, M. Rasekh, M. Edirisinghe, Macromol. Mater. Eng. 295, 315–319 (2010)
Z.W. Ma, M. Kotaki, R. Inai, S. Ramakrishna, Tissue Eng. 11, 101 (2005)
M. Shin, H. Yoshimoto, J.P. Vacanti, Tissue Eng. 10, 33 (2004)
T. Sun, S. Mai, D. Norton, J.W. Haycock, A.J. Ryan, S. Macneil, Tissue Eng. 11, 1023 (2005)
A. Subramanian, D. Vu, G.F. Larsen, H.-Y. Lin, J. Biomater. Sci., Polym. Ed. 16, 861 (2005)
A. Thorvaldsson, H. Stenhamre, P. Gatenholm, P. Walkenström, Biomacromolecules 9, 1044 (2008)
Y.M. Ju, J.S. Choi, A. Atala, J.J. Yoo, S.J. Lee, Biomaterials 31, 4313 (2010)
J. Xie, M.R. MacEwan, A.G. Schwartz, Y. Xia, Nanoscale 2, 35 (2010)
S.J. Kim, D.H. Jang, W.H. Park, B.-M. Min, Polymer 51, 1320 (2010)
T.J. Sill, H.A. von Recum, Biomaterials 29, 1989 (2008)
J.-F. Zhang, D.-Z. Yang, J. Nie, Polym. Adv. Technol. 19, 1150 (2008)
J.K. Hong, S.V. Madihally, Acta Biomat. 6, 4734 (2010)
M.R. Badrossamay, H.A. McIlwee, J.A. Goss, K.K. Parker, Nano Lett. 10, 2257 (2010)
R. Tzezana, E. Zussman, S. Levenberg, Tissue Eng. Part C Methods 14, 281 (2008)
S. Igarashi, J. Tanaka, H. Kobayashi, J. Nanosci. Nanotechnol. 7, 814 (2007)
S. Yan, L. Xiaoqiang, T. Lianjiang, H. Chen, M. Xiumei, Polymer 50, 4212 (2009)
A.J. Hines, R.N. Maddox, Mass Transfer: Fundamental and Applications (Prentice Hall International, Englewood Cliffs, 1985)
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Hong, S., Kim, G. Fabrication of size-controlled three-dimensional structures consisting of electrohydrodynamically produced polycaprolactone micro/nanofibers. Appl. Phys. A 103, 1009–1014 (2011). https://doi.org/10.1007/s00339-011-6381-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00339-011-6381-5