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A potential human axonemal dynein heavy-chain gene maps to 17q25

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References

  • Afzelius BA (1976) A human syndrome caused by immotile cilia. Science 193, 317–319

    Article  PubMed  CAS  Google Scholar 

  • Afzelius BA (1979) The immotile-cilia syndrome and other ciliary diseases. Int Rev Exp Pathol 19, 1–43

    PubMed  CAS  Google Scholar 

  • Afzelius BA, Mossberg B (1989) Immotile-cilia syndrome including Kartagener syndrome. In The Metabolic Basis of Inherited Disease, CR Scriver, AL Beaudet, WS Sly, D Valle, eds. (New York: McGraw-Hill), pp 2739–2750

    Google Scholar 

  • Boehnke M (1992) Multipoint analysis for radiation hybrid mapping. Ann Med 24, 383–386

    Article  PubMed  CAS  Google Scholar 

  • Brueckner M, D’Eustachio P, Horwich AL (1989) Linkage mapping of a mouse gene iv, that controls left-right asymmetry of the heart and viscera. Proc Natl Acad Sci USA 86, 5035–5038

    Article  PubMed  CAS  Google Scholar 

  • Devereux J, Haeberli P, Smithies O (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res 12, 387–395

    Article  PubMed  CAS  Google Scholar 

  • Dick T, Ray K, Salz MK, Chia W (1996) Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster. Mol Cell Biol 16, 1966–1977

    PubMed  CAS  Google Scholar 

  • Drews U (1995) In Color Atlas of Embryology, (Stuttgart: Georg Thieme Verlag), p 312

    Google Scholar 

  • Feinberg AP, Vogelstein B (1983) A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132, 6–13

    Article  PubMed  CAS  Google Scholar 

  • Foster JW, Schafer AJ, Critcher R, Spillett DJ, Feakes RW, Walter MA, Dominguez-Steglich M, Guioli S, Brook JD, Goodfellow PN (1996) A high resolution whole genome radiation hybrid map of human chromosome 17q22-25.3, across the genes for GH and TK. Genomics 33, 185–192

    Article  PubMed  CAS  Google Scholar 

  • Gibbons BH, Asai DJ, Tank W-JY, Hays TS, Gibbons IR (1994) Phylogeny and expression of axonemal and cytoplasmic dynein genes in sea urchins. Mol Biol Cell 5, 57–70

    PubMed  CAS  Google Scholar 

  • Gibbons IR, Gibbons BH, Mocz G, Asai DJ (1991) Multiple nucleotidebinding sites in the sequences of dynein β heavy chain. Nature 352, 640–643

    Article  PubMed  CAS  Google Scholar 

  • Hanauer A, Mandel JL (1984) The glyceraldehyde 3-phosphate dehydrogenase gene family: structure of a human cDNA and of an X chromosome linked pseudogene; amazing complexity of the gene family in mouse. EMBO J 3, 2627–2633

    PubMed  CAS  Google Scholar 

  • Handel MA, Kennedy JR (1984) Situs inversus in homozygous mice without immotile cilia. J Hered 75, 498

    PubMed  CAS  Google Scholar 

  • Heald R, Tourenbize, R, Blank T, Sandaltzopoulos R, Becker P, Hyman A, Karsenti E (1996) Self-organization of microtubules in bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature 382, 420–425

    Article  PubMed  CAS  Google Scholar 

  • Mikami A, Paschal BM, Mazumdar M, Vallee RB (1993) Molecular cloning of the retrograde transport motor cytoplasmic dynein (MAP 1C). Neuron 10, 787–796

    Article  PubMed  CAS  Google Scholar 

  • Milisav I, Jones MH, Affara NA (1996) Characterisation of a novel human dynein-related gene that is specifically expressed in testis. Mammal Genome 7, 667–672

    Article  CAS  Google Scholar 

  • Narayan D, Desai T, Banks A, Patanjali SR, Ravikumar TS, Ward DC (1994) Localization of the human cytoplasmic dynein heavy chain (DNECL) to 14qter by fluorescence in situ hybridization. Genomics 22, 660–661

    Article  PubMed  CAS  Google Scholar 

  • Ogawa K (1991) Four ATP-binding sites in the midregion of the β heavy chain of dynein. Nature 352, 643–645

    Article  PubMed  CAS  Google Scholar 

  • Pearson WR, Lipman DJ (1988) Improved tools for biological sequence comparison. Proc Natl Acad Sci USA 85, 2444–2448

    Article  PubMed  CAS  Google Scholar 

  • Sambrook J, Fritsch EF, Maniatis T (1989) Analysis of RNA. In Molecular Cloning, A Laboratory Manual, 2nd ed. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press), pp 7.37–7.45

    Google Scholar 

  • Schidlow DV, Katz SM (1983) Immotile cilia syndrome. N Eng J Med, 308, 595

    CAS  Google Scholar 

  • Sudo K, Chinen K, Nakamura Y (1994) 2058 expressed sequence tags (ESTs) from a human fetal lung cDNA library. Genomics 24, 276–279

    Article  PubMed  CAS  Google Scholar 

  • Tanaka Y, Zhang Z, Hirokawa N (1995) Identification and molecular evolution of new dynein-like protein sequences in rat brain. J Cell Sci 108, 1883–1893

    PubMed  CAS  Google Scholar 

  • Vaisberg EA, Koonce MP, McIntosh JR (1993) Cytoplasmic dynein plays a role in mammalian mitotic spindle formation. J Cell Biol 123, 849–858

    Article  PubMed  CAS  Google Scholar 

  • Vaughan KT, Mikami A, Paschal BM, Holzbauer ELF, Hughes SM, Echeverri CJ, Moore KJ, Gilbert DJ, Copeland NG, Jenkins NA, Vallee RB (1996) Multiple mouse chromosomal loci for dynein-based motility. Genomics 36, 29–38

    Article  PubMed  CAS  Google Scholar 

  • Wahl GM, Lewis KA, Ruiz JC, Rothenberg B, Zhao J, Evans GA (1987) Cosmid vectors for rapid genome walking, restriction mapping and gene transfer. Proc Natl Acad Sci USA 84, 2160–2164

    Article  PubMed  CAS  Google Scholar 

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  1. Department of Pathology, Human Molecular Genetics Group, University of Cambridge, Tennis Court Road, CB2 1QP, Cambridge, UK

    Irina Milisav & Nabeel A. Affara

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  1. Irina Milisav
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  2. Nabeel A. Affara
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Milisav, I., Affara, N.A. A potential human axonemal dynein heavy-chain gene maps to 17q25. Mammalian Genome 9, 404–407 (1998). https://doi.org/10.1007/s003359900782

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  • DOI: https://doi.org/10.1007/s003359900782

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