Skip to main content
Log in

The open brain (opb) mutation maps to mouse chromosome 1

  • Short Communication
  • Published:
Mammalian Genome Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Chromosome 1 Committee, 1997 Report (1996) Encyclopedia of the mouse genome, Mouse Informatics project. The Jackson Laboratory, Bar Harbor, Me. World Wide Web (URL: http://www.informatics.jax.org)

  • Copeland NG, Silan CM, Kingsley DM, Jenkins NA, Cannizzaro LA, Croce CM, Huebner K, Sims JE (1991) Chromosomal localization of murine and human Il-1 receptor genes. Genomics 9, 44–50

    Article  PubMed  CAS  Google Scholar 

  • Copp AJ, Brook FA, Estibeiro P, Shum ASW, Cockroft DL (1990) The embryonic development of mammalian neural tube defects. Progr Neurobiol 35, 363–103

    Article  CAS  Google Scholar 

  • Darling S (1996) Mice as models of human developmental disorders: natural and artificial mutants. Curr Opin Genet Dev 6, 289–294

    Article  PubMed  CAS  Google Scholar 

  • Dietrich WF, Miller JC, Steen JC, Merchant M, Damron D, Nahf R, Gross A, Joyce DC, Wessel M, Dredge RD, Marquis A, Stein LD, Goodman N, Page N, Lander ES (1994) A genetic map of the mouse with 4006 simple sequence length polymorphisms. Nature Genet 7, 220–225

    Article  PubMed  CAS  Google Scholar 

  • Elliott RW (1986) A mouse “minisatellite”. Mouse News Lett 74, 115–117

    Google Scholar 

  • Evans C, Searle AG, Schinzel AA, Winter RM (1996) The dysmorphic human mouse homology database (DHMHD): an interactive world-wide web resource for gene mapping. J Med Genet 33, 289–294

    Article  PubMed  CAS  Google Scholar 

  • Favor J, Sandaluche R, Neuhäuser-Klaus A, Pretsch W, Chaterjee B, Senft E, Wurst W, Blanquet V, Grimes P, Spörle R, Schughart K (1996) The mouse Pax2 1Neu mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney. Proc Natl Acad Sci USA 93, 13870–13875

    Article  PubMed  CAS  Google Scholar 

  • Günther T, Struwe M, Aguzzi A, Schughart K (1994) open brain, a new mouse mutant with severe neural tube defects, shows altered gene expression patterns in the developing spinal cord. Development 120, 3119–3130

    PubMed  Google Scholar 

  • Liao X, Ma C, Trask B, Massa H, Gilbert DJ, Staudt LM, Jenkins NA, Copeland NG (1996) LAF4 maps to mouse Chromosome 1 and human Chromosome 2qll.2-ql2. Mamm Genome 7, 467–468

    Article  PubMed  CAS  Google Scholar 

  • McMahan CJ, Slack JL, Mosley B, Cosman D, Lupton SD, Brunton LL, Grubin CE, Wignall JM, Jenkins NA, Brannan CI, Copeland NG, Huebner K, Croce CM, Cannizzaro LA, Benjamin D, Dower SK, Spriggs MK, Sims JE (1991) A novel Il-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J 10, 2821–2832

    PubMed  CAS  Google Scholar 

  • Manly KF (1993) A Macintosh program for storage and analysis of experimental genetic mapping data. Mamm Genome 4, 303–313

    Article  PubMed  CAS  Google Scholar 

  • The Mouse Genome Database (1996) The Jackson Laboratory, Bar Harbor, ME. World Wide Web (URL: http://www.informatics.jax.org/mgd.html)

  • Spörle R, Günther T, Struwe M, Schughart K (1996) Severe defects in the formation of epaxial musculature in open brain (opb) mutant mouse embryos. Development 122, 79–86

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Günther, T., Spörle, R. & Schughart, K. The open brain (opb) mutation maps to mouse chromosome 1. Mammalian Genome 8, 583–585 (1997). https://doi.org/10.1007/s003359900509

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s003359900509

Keywords

Navigation