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An answer to a complex problem: cloning the mouse t-complex responder

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Abstract.

The t-complex is maintained in wild mouse populations by its high transmission (up to 99%) from heterozygous males and provides an example of ``meiotic drive''. Its molecular basis has remained obscure despite long and intensive study. In a major advance, the t-complex responder gene, thought to be the key gene on which several distorters act, has now been cloned.

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Received: 14 April 2000 / Accepted: 4 May 2000

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Lyon, M. An answer to a complex problem: cloning the mouse t-complex responder. Incorporating Mouse Genome 11, 817–819 (2000). https://doi.org/10.1007/s003350010153

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  • DOI: https://doi.org/10.1007/s003350010153

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