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Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans

Mammalian Genome volume 23, pages 641–652 (2012)Cite this article

Abstract

The International Mouse Phenotyping Consortium (IMPC) (http://www.mousephenotype.org) will reveal the pleiotropic functions of every gene in the mouse genome and uncover the wider role of genetic loci within diverse biological systems. Comprehensive informatics solutions are vital to ensuring that this vast array of data is captured in a standardised manner and made accessible to the scientific community for interrogation and analysis. Here we review the existing EuroPhenome and WTSI phenotype informatics systems and the IKMC portal, and present plans for extending these systems and lessons learned to the development of a robust IMPC informatics infrastructure.

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Authors and Affiliations

  1. Mammalian Genetics Unit, Medical Research Council Harwell, Harwell, Oxfordshire, OX11 0RD, UK

    Ann-Marie Mallon, Hugh Morgan & Steve D. M. Brown

  2. The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, UK

    Vivek Iyer, David Melvin & William C. Skarnes

  3. European Bioinformatics Institute, Hinxton, Cambridge, CB10 1ST, UK

    Helen Parkinson & Paul Flicek

Authors
  1. Ann-Marie Mallon
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  2. Vivek Iyer
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  3. David Melvin
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  4. Hugh Morgan
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  5. Helen Parkinson
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  6. Steve D. M. Brown
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  7. Paul Flicek
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  8. William C. Skarnes
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Correspondence to Ann-Marie Mallon.

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Mallon, AM., Iyer, V., Melvin, D. et al. Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans. Mamm Genome 23, 641–652 (2012). https://doi.org/10.1007/s00335-012-9428-9

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  • DOI: https://doi.org/10.1007/s00335-012-9428-9

Keywords

  • Laboratory Information Management System
  • Mammalian Phenotype
  • Wellcome Trust Sanger Institute
  • Data Coordination Centre
  • Phenotyping Centre