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The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping


Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.

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Correspondence to Steve D. M. Brown.

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Brown, S.D.M., Moore, M.W. The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping. Mamm Genome 23, 632–640 (2012).

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  • Phenotype Ontology
  • Wellcome Trust Sanger Institute
  • Phenotype Annotation
  • Mandatory Test
  • Data Coordination Centre