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European Radiology

, Volume 12, Issue 3, pp 545–548 | Cite as

Imaging findings in the rare catastrophic variant of the primary antiphospholipid syndrome

  • Christina Thuerl
  • Carsten Altehoefer
  • Alexandros Spyridonidis
  • Jörg Laubenberger
Hepatobiliary-Pancreas

Abstract.

We report imaging findings in a case of the rare catastrophic variant of antiphospholipid syndrome (CAPS) characterized by widespread microvascular occlusions, which may lead to multiple organ failure. We present a case of a 66-year-old woman with bone marrow necrosis, acute acalculous cholecystitis (AAC), focal liver necrosis, subtle patchy splenic infarctions, and bilateral adrenal infarction. The demonstration of multiple microvascular organ involvement (three or more) is crucial for the diagnosis of the catastrophic variant of APS. This can be performed radiologically intra-vitam. Imaging can even reveal subclinical microinfarctions, which are often only diagnosed at autopsy.

Catastrophic antiphospholipid syndrome Imaging Bone marrow necrosis Acalculous cholecystitis Adrenal infarction 

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Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • Christina Thuerl
    • 1
  • Carsten Altehoefer
    • 1
  • Alexandros Spyridonidis
    • 2
  • Jörg Laubenberger
    • 1
  1. 1.Department of Radiology, University of Freiburg, Hugstetter Strasse 55, 79106 Freiburg, GermanyGermany
  2. 2.Department of Innere Medizin I, University of Freiburg, Hugstetter Strasse 55, 79106 Freiburg, GermanyGermany

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