Abstract
The number of scientific papers on iodinated contrast media is declining. Indeed, comparative trials between high-osmolality and low-osmolality agents largely showed the higher safety and tolerability of the latter, and this is no longer a matter of discussion. Only financial constraints could prevent a total conversion to low-osmolality agents. Research comparing low-osmolality (nonionic monomers, ionic dimer) and iso-osmolality contrast media (nonionic dimers) are still ongoing. Both classes of nonionic compounds proved safer than the ionic dimer. The relative merits of nonionic monomers and nonionic dimers are a matter for debate, and criteria for a selective use of different agents for different procedures could be discussed.
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Received: 26 June 2000 Accepted: 14 July 2000
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Stacul, F. Current iodinated contrast media. Eur Radiol 11, 690–697 (2001). https://doi.org/10.1007/s003300000620
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DOI: https://doi.org/10.1007/s003300000620