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Table 3 Distribution of the number and timing of scans routinely performed during adjuvant temozolomide (TMZ). Also shown are the standardised protocols implemented when there is suspected progression or new clinical symptoms

From: Glioblastoma post-operative imaging in neuro-oncology: current UK practice (GIN CUP study)

Number of scans during adjuvant period (not including post-cycle 6 TMZ) Number of centres, n (%)
  0 3 (10%)
  1 7 (23%)
  2 12 (39%)
  3 4 (13%)
  No standardised protocol 5 (16%)
Timing of first post-chemoradiotherapy scan Number of centres, n (%)
  4 weeks 12 (39%)
  8 weeks 1 (3%)
  12 weeks 10 (32%)
  End of TMZ cycle 6 only 3 (10%)
  No standardised protocol 5 (16%)
Protocol in suspected progression Number of centres, n (%)
  Additional imaging at 4–6 weeks 14 (45%)
  Additional imaging over 4–12 weeks 8 (26%)
  No standardised protocol 6 (19%)
  No routine scans performed during adjuvant period 3 (10%)
Protocol if symptomatic during this period Number of centres, n (%)
  Initial CT, followed by MRI 11 (35%)
  MRI 20 (65%)