|
HC vs. NMOSD-ON
|
Area
|
Width
|
Left
Height
|
Central
Height
|
Right
Height
|
Total
Height
|
|
AUC
|
0.95
|
0.64
|
0.90
|
0.95
|
0.92
|
0.94
|
|
95% CI
|
0.91–1.00
|
0.49–0.79
|
0.81–0.98
|
0.89–1.00
|
0.85–1.00
|
0.87–1.00
|
|
p value AUC comparison
|
–
|
< 0.01
|
0.02
|
0.78
|
0.16
|
0.40
|
|
HC vs. NMOSD-NON
|
Area
|
Width
|
Left
Height
|
Central
Height
|
Right
Height
|
Total
Height
|
|
AUC
|
0.78
|
0.55
|
0.74
|
0.80
|
0.78
|
0.77
|
|
95% CI
|
0.57–0.92
|
0.38–0.73
|
0.52–0.88
|
0.59–0.95
|
0.62–0.94
|
0.60–0.94
|
|
p value AUC comparison
|
–
|
0.08
|
0.31
|
0.49
|
0.93
|
0.77
|
|
NMOSD-ON vs. NMOSD-NON
|
Area
|
Width
|
Left
Height
|
Central
Height
|
Right
Height
|
Total
Height
|
|
AUC
|
0.81
|
0.63
|
0.71
|
0.74
|
0.76
|
0.76
|
|
95% CI
|
0.69–0.95
|
0.46–0.80
|
0.54–0.89
|
0.59–0.90
|
0.57–0.90
|
0.60–0.92
|
|
p value AUC comparison
|
–
|
0.08
|
0.06
|
0.19
|
0.29
|
0.14
|
- Shown are area under the curve (AUC), 95% confidence interval (CI), and p value for AUC comparison using area as reference. HC = healthy controls; NMOSD-ON = neuromyelitis optica patients with history of optic neuritis; NMOSD-NON = neuromyelitis optica patients without history of optic neuritis