|
Number
|
37
|
14
|
25
|
–
|
|
Age, years (mean, SD)
|
47.8 (12.6)
|
53.8 (12.5)
|
48.09 (14.9)
|
0.33
|
|
Sex (F/M) (% female)
|
30/7 (81%)
|
14/0 (100%)
|
21/4 (84%)
|
0.22
|
|
Disease duration, years (median, range)
|
–
|
–
|
7.1 (3–34.1)
| |
|
Number of ON (median, range)
|
–
|
–
|
2 (1–12)
|
–
|
|
Time since first ON, years (median, range)
|
–
|
–
|
6.9 (3.4–32.2)
|
–
|
|
Time since last ON, years (median, range)
|
–
|
–
|
4.9 (0.5–13.2)
|
–
|
|
ON involvement, bilateral/unilateral
|
–
|
–
|
11/14
(8 right/6 left)
|
–
|
|
Optic nerve diameter, mm (mean, SD)
|
8.37 (0.50)
|
8.13 (0.90)
|
7.06 (1.23)
|
< 0.001
|
|
pRNFL, μm (mean, SD)
|
91.99 (15.10)
|
97.96 (10.13)
|
67.57 (17.92)
|
< 0.001
|
|
GCIPL mm3 (mean, SD)
|
1.83 (0.28)
|
1.88 (0.14)
|
1.49 (0.25)
|
< 0.001
|
|
Visual acuity, logMAR (mean, SD)
|
− 0.01 (0.21)
|
−0.15 (0.21)
|
0.30 (0.63)
|
0.04
|
|
Visual Functional System Score (median, range)
|
–
|
0 (0–2)
|
1 (0–6)
|
< 0.001
|
|
EDSS (median, range)
|
–
|
3 (1–7)
|
4 (0–6.5)
|
0.71
|