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Safety of exposure to high static magnetic fields (2 T–12 T): a study on mice

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We aimed to evaluate the biological effects of high static magnetic field (HiSMF, 2–12 Tesla [T]) exposure on mice in a stable and effective breeding environment in the chamber of a superconducting magnet.


C57BL/6 mice were bred in the geomagnetic field and HiSMF with different magnetic field strengths (2–4 T, 6–8 T, and 10–12 T) for 28 days. The body weight, blood indices, organ coefficients, and histomorphology of major organs were analyzed.


The results showed that the HiSMF had no significant effect on the body weight, organ coefficients, or histomorphology of major organs in mice. The HiSMF had no effect on most routine blood and biochemical indices, but the value of the mean corpuscular hemoglobin (MCH) was increased in the 2–4 T group compared with that of the other groups, and the uric acid level (UA) was decreased in the three HiSMF groups compared with that of the control group.


The C57BL/6 mice were not affected when they were exposed to different HiSMF environments for 28 days.

Key Points

No physiological problems were observed in mice with long-term whole-body exposure to HiSMF.

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Alanine aminotransferase


Blood urea nitrogen


Total serum cholesterol




Computed tomography


Geomagnetic field




High static magnetic field


Mean corpuscular hemoglobin


Mean corpuscular volume


Magnetic resonance imaging


Platelet distribution width


Platelet count


Red blood cell count


Coefficient variation of red blood cell volume distribution width


Static magnetic field


Total bilirubin




Uric acid


White blood cell count


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This study has received funding by the Science and Technology Planning Project of Science, Technology and Innovation Commission of Shenzhen Municipality of China (JCYJ20170412140904406), and National Natural Science Foundation of China (51777171).

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Correspondence to Peng Shang.

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The scientific guarantor of this publication is Peng Shang, PhD.

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The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.

Statistics and biometry

One of the authors has significant statistical expertise.

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Institutional Review Board approval was obtained.


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Wang, S., Luo, J., Lv, H. et al. Safety of exposure to high static magnetic fields (2 T–12 T): a study on mice. Eur Radiol 29, 6029–6037 (2019).

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