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Modified CAIPIRINHA-VIBE without view-sharing on gadoxetic acid–enhanced multi-arterial phase MR imaging for diagnosing hepatocellular carcinoma: comparison with the CAIPIRINHA-Dixon-TWIST-VIBE

  • Magnetic Resonance
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Abstract

Purpose

We evaluated the detection rate and degree of motion artifact of the modified CAIPIRINHA-VIBE (mC-VIBE) without view-sharing and compare them with the CAIPIRINHA-Dixon-TWIST-VIBE (CDT-VIBE) with view-sharing on multi-arterial gadoxetic acid–enhanced liver MRI in the assessment of hepatocellular carcinoma (HCC).

Material and methods

We retrospectively identified 114 pathological-proven hepatic tumors in 114 patients with risk of HCC who underwent multi-arterial gadoxetic acid–enhanced MRI between June 2016 and June 2018. All patients underwent triple arterial phase imaging using the mC-VIBE without view-sharing (54 patients; 49 HCCs and 5 non-HCCs) or the CDT-VIBE with view-sharing (60 patients; 55 HCCs and 5 non-HCCs). We compared the detection rate of two sequences for HCC, with reference to LI-RADS.V.2017. We also compared the mean motion scores and proportions of transient severe motion (TSM) in two sequences.

Result

For the examination using the mC-VIBE, the HCC-detection rate was significantly higher, compared with that using CDT-VIBE (93.9% [46/49] vs 80.0% [44/55], respectively; p = 0.047). For the examination with the mC-VIBE, mean motion scores were significantly lower compared with those of CDT-VIBE for all multi-arterial phases (1.21, 1.19, and 1.15 vs. 1.82, 1.85, and 1.84, respectively; p < 0.001 for all three comparisons). The proportion of TSM in the CDT-VIBE was significantly higher than that in the mC-VIBE (15.0% [9/60] vs 0.0% [0/54], respectively; p = 0.003).

Conclusion

In multi-arterial phase gadoxetic acid–enhanced MRI, the mC-VIBE sequence without view-sharing has slightly higher HCC-detection rate and fewer motion artifacts compared with CDT-VIBE with view-sharing.

Key Points

• Multi-arterial phase using the mC-VIBE without view-sharing can overcome motion artifacts, resulting in providing optimal arterial phase imaging.

• The HCC-detection rate is slightly higher with the mC-VIBE vs. CAIPIRINHA-Dixon-TWIST-VIBE with view-sharing (CDT-VIBE).

• View-sharing of CDT-VIBE in the multi-arterial phase is associated with increased frequency of TSM.

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Abbreviations

APHE:

Arterial phase hyperenhancement

CAIPIRINHA:

Controlled aliasing in parallel imaging results in higher acceleration factor

CDT-VIBE:

CAIPIRINHA-Dixon-TWIST-VIBE

mC-VIBE:

Modified CAIPIRINA VIBE

TSM:

Transient severe motion

TWIST:

Time-resolved angiography with interleaved stochastic trajectories

VIBE:

Volumetric interpolated breath-hold examination

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The authors state that this work has not received any funding.

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Authors and Affiliations

  1. Department of Radiology, Biomedical Research Institute, Pusan National University Hospital, and Pusan National University School of Medicine, 179 Gudeok-ro, Seo-gu, Busan, 49241, South Korea

    Seung Baek Hong, Nam Kyung Lee & Suk Kim

  2. Department of Surgery, Biomedical Research Institute, Pusan National University Hospital, and Pusan National University School of Medicine, Busan, South Korea

    Hyeong Il Seo

  3. Department of Surgery, Biomedical Research Institute, Pusan National University Yangsan Hospital, and Pusan National University School of Medicine, Busan, South Korea

    Hyun Sung Kim

  4. Department of Internal Medicine, Biomedical Research Institute, Pusan National University Hospital, and Pusan National University School of Medicine, Busan, South Korea

    Dong Uk Kim

  5. Department of Radiology, Biomedical Research Institute, Pusan National University Yangsan Hospital, and Pusan National University School of Medicine, Busan, South Korea

    Tae Un Kim & Hwa Seong Ryu

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  1. Seung Baek Hong
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Correspondence to Nam Kyung Lee.

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The scientific guarantor of this publication is Nam Kyung Lee.

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The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

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Hong, S.B., Lee, N.K., Kim, S. et al. Modified CAIPIRINHA-VIBE without view-sharing on gadoxetic acid–enhanced multi-arterial phase MR imaging for diagnosing hepatocellular carcinoma: comparison with the CAIPIRINHA-Dixon-TWIST-VIBE. Eur Radiol 29, 3574–3583 (2019). https://doi.org/10.1007/s00330-019-06095-x

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