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Real-time MR-guided brain biopsy using 1.0-T open MRI scanner

  • Interventional
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

Objectives

To evaluate the safety, feasibility and diagnostic performance of real-time MR-guided brain biopsy using a 1.0-T open MRI scanner.

Methods

Medical records of 86 consecutive participants who underwent brain biopsy under the guidance of a 1.0-T open MRI scanner with real-time and MR fluoroscopy techniques were evaluated retrospectively. All procedures were performed under local anaesthesia and intravenous conscious sedation. Diagnostic yield, diagnostic accuracy, complication rate and procedure duration were assessed. The lesions were divided into two groups according to maximum diameters: ≤ 1.5 cm (n = 16) and > 1.5 cm (n = 70). The two groups were compared using Fisher’s exact test.

Results

Diagnostic yield and diagnostic accuracy were 95.3% and 94.2%, respectively. The diagnostic yield of lesions ≤ 1.5 cm and > 1.5 cm were 93.8% and 95.7%, respectively. There was no significant difference in diagnostic yield between the two groups (p > 0.05). Mean procedure duration was 41 ± 5 min (range 33–49 min). All biopsy needles were placed with one pass. Complication rate was 3.5% (3/86). Minor complications included three cases of a small amount of haemorrhage. No serious complications were observed.

Conclusions

Real-time MR-guided brain biopsy using a 1.0-T open MRI scanner is a safe, feasible and accurate diagnostic technique for pathological diagnosis of brain lesions. The procedure duration is shortened and biopsy work flow is simplified. It could be considered as an alternative for brain biopsy.

Key Points

• Real-time MRI-guided brain biopsy using a 1.0-T open MRI scanner is safe, feasible and accurate.

• No serious complications occurred in real-time MRI-guided brain biopsy.

• Procedure duration is shortened and biopsy work flow is simplified.

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Abbreviations

NeuroICU:

Neuro intensive care unit

RF:

Radiofrequency

T1W-TSE:

T1-weighted turbo spin echo

T2W-TSE:

T2-weighted turbo spin echo

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Funding

This study has received funding by Shandong Science and technology development plan (2014GGH218005).

Author information

Authors and Affiliations

  1. Department of Interventional MRI, Shandong Medical Imaging Research Institute affiliated to Shandong University, Shandong Key Laboratory of Advanced Medical Imaging Technologies and Applications, Jinan, Shandong, People’s Republic of China

    Xiangmeng He, Ming Liu, Yujun Xu & Chengli Li

  2. Department of Minimally Invasive Tumor, Tai’an Central Hospital, Tai’an, Shandong, People’s Republic of China

    Chao Liu

  3. Department of Hemodialysis, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of China

    Jing Fang

  4. Department of Medical Imaging and Interventional Radiology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, People’s Republic of China

    Ligang Wang

  5. Department of Intervention, Shanghai Jiaotong University Affiliated Sixth People’s Hospital South Campus, Shanghai, People’s Republic of China

    Jianfeng Xiang

  6. South Western Finland Imaging Centre, Turku University Hospital, Turku, Finland

    Roberto Blanco Sequeiros

Authors
  1. Xiangmeng He
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  2. Ming Liu
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  3. Chao Liu
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  4. Jing Fang
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  5. Yujun Xu
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  6. Ligang Wang
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  7. Jianfeng Xiang
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  8. Roberto Blanco Sequeiros
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  9. Chengli Li
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Corresponding author

Correspondence to Chengli Li.

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Guarantor

The scientific guarantor of this publication is Chengli Li.

Conflict of interest

The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.

Statistics and biometry

All authors kindly provided statistical advice for this manuscript.

No complex statistical methods were necessary for this paper.

Informed consent

Written informed consent was obtained from all subjects (patients) in this study.

Ethical approval

Institutional review board approval was obtained.

Methodology

• retrospective

• diagnostic or prognostic study

• performed at one institution

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Cite this article

He, X., Liu, M., Liu, C. et al. Real-time MR-guided brain biopsy using 1.0-T open MRI scanner. Eur Radiol 29, 85–92 (2019). https://doi.org/10.1007/s00330-018-5531-y

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  • DOI: https://doi.org/10.1007/s00330-018-5531-y

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