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Preoperative localisation of pulmonary ground-glass opacity using medical adhesive before thoracoscopic resection

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Abstract

Objectives

To evaluate the safety and efficiency of computed tomography (CT)-guided medical adhesive, α-cyanoacrylate, for preoperative localisation of pulmonary ground-glass opacity (GGO) used for guiding the video-assisted thoracoscopic surgical (VATS) excision

Methods

The procedure was performed on 188 consecutive patients with solitary GGO (pure GGO = 90 cases; mixed GGO = 98 cases) prior to the thoracoscopic procedure. The complications and efficacy of this method were analysed. The resected GGO was analysed pathologically.

Results

The mean duration of the procedure was 16.3 ± 5.2 min. The preoperative localisation was 100% successful. All GGOs were successfully resected by VATS. Asymptomatic pneumothorax was developed in 16/188 patients (8.5%) and mild pulmonary haemorrhage occurred in 15 cases (7.9%) post-localisation. None of the patients required any further treatment for the complications.

Conclusion

Preoperative localisation using CT-guided medical adhesive, α-cyanoacrylate, is a safe and short-duration procedure, with high accuracy and success rates with respect to VATS resection of GGO.

Key Points

• Preoperative localisation is crucial for successful resection of GGO by VATS.

• Preoperative adhesive localisation provides an up to 100% successful localisation rate with few complications.

• Preoperative adhesive localisation enabled VATS resection in 100% of the GGO.

• Preoperative adhesive localisation is safe and effective for VATS resection of GGO.

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Abbreviations

GGO:

Ground-glass opacity

VATS:

Video-assisted thoracoscopic surgery

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Funding

This study has received funding from the Medical Scientific Research Foundation of Guangdong Province, China (A2016410), and National Natural Science Foundation of China (81601457)

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Author notes

  1. Ren-li Cen and Fei Cui contributed equally to this work.

Authors and Affiliations

  1. Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No 151, Guangzhou, China

    Ren-li Cen, Qi Wan, Ling Chen, Xiao-yan Huang, Jia-xuan Zhou & Qing-si Zeng

  2. Department of Thoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Yanjiangxilu No 151, Guangzhou, China

    Fei Cui, Shu-ben Li & Jian-xing He

Authors
  1. Ren-li Cen
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  2. Fei Cui
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  3. Qi Wan
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  4. Ling Chen
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  5. Xiao-yan Huang
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  6. Jia-xuan Zhou
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  7. Shu-ben Li
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  8. Qing-si Zeng
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  9. Jian-xing He
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Corresponding authors

Correspondence to Qing-si Zeng or Jian-xing He.

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Guarantor

The scientific guarantor of this publication is Qingsi Zeng.

Conflict of interest

The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

Statistics and biometry

No complex statistical methods were necessary for this paper.

Informed consent

Written informed consent was waived by the Institutional Review Board.

Ethical approval

Institutional Review Board approval was obtained.

Methodology

• retrospective

• observational

• performed at one institution

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Cen, Rl., Cui, F., Wan, Q. et al. Preoperative localisation of pulmonary ground-glass opacity using medical adhesive before thoracoscopic resection. Eur Radiol 28, 4048–4052 (2018). https://doi.org/10.1007/s00330-018-5394-2

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  • DOI: https://doi.org/10.1007/s00330-018-5394-2

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