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European Radiology

, Volume 28, Issue 10, pp 4151–4162 | Cite as

Comparison of T2 Relaxation Values in Subtalar Cartilage between Patients with Lateral Instability of the Ankle Joint and Healthy Volunteers

  • Hyun Su Kim
  • Young Cheol Yoon
  • Ki Sun Sung
  • Min-Ji Kim
  • Soohyun Ahn
Musculoskeletal

Abstract

Purpose

To evaluate the difference between T2 relaxation values of the subtalar cartilage in lateral ankle instability patients and healthy volunteers.

Materials and Methods

This institutional review board-approved study included 27 preoperative magnetic resonance imaging (MRI) examinations of 26 patients who underwent Broström operations. Data of previously enrolled healthy volunteers (12 volunteers, 13 MRIs) were used as controls. Two radiologists independently measured T2 values in eight posterior subtalar joint cartilage compartments: central calcaneus anterior (CCA) and posterior (CCP), central talus anterior (CTA) and posterior (CTP), lateral calcaneus anterior (LCA) and posterior (LCP), and lateral talus anterior (LTA) and posterior (LTP). Patient and control values were compared using linear regression analysis. Inter- and intraobserver agreement was calculated.

Results

Mean T2 values were significantly higher in the patient group in all measurements of subtalar joint cartilage compartments (p < 0.05) except that in LTP (p = 0.085) measured by reviewer 1. Both inter- and intraobserver agreements were excellent.

Conclusions

The T2 relaxation values of the subtalar cartilage were significantly higher in lateral ankle instability patients compared with those of controls.

Key Points

• Subtalar cartilage T2 values are increased in patients with lateral ankle instability.

• This trend was demonstrated regardless of the presence of talar dome cartilage lesions.

• Inter-and intraobserver agreements were excellent (intraclass coefficient range, 0.765-0.951) in subtalar cartilage T2 mapping.

Keywords

T2 relaxation mapping Subtalar joint Lateral instability of the ankle joint 

Abbreviations

CCA

Central calcaneus anterior

CCP

Central calcaneus posterior

CTA

Central talus anterior

CTP

Central talus posterior

LCA

Lateral calcaneus anterior

LCP

Lateral calcaneus posterior

LTA

Lateral talus anterior

LTP

Lateral talus posterior

MRI

Magnetic resonance imaging

Notes

Funding

The authors state that this work has not received any funding.

Compliance with ethical standards

Guarantor

The scientific guarantor of this publication is Young Cheol Yoon.

Conflict of interest

The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.

Statistics and biometry

Min-Ji Kim and Soohyun Ahn kindly provided statistical advice for this manuscript.

Informed consent

Written informed consent was waived by the Institutional Review Board.

Ethical approval

Institutional Review Board approval was obtained.

Study subjects or cohorts overlap

Some study subjects or cohorts have been previously reported in the article titled “T2 relaxation values of the talar trochlear articular cartilage: comparison between patients with lateral instability of the ankle joint and healthy volunteers” (American Journal of Roentgenology, January 2016, Volume 206, Number 1). The subjects in this previously published article, 12 patients (13 ankle MRIs) and 12 healthy volunteers (13 ankle MRIs), were all included in the 38 subjects (40 MRIs) of our manuscript. The previously published article focused on T2 relaxation values in talar trochlear cartilage and their potential relation with lateral ankle instability. In the submitted manuscript, we reported our study result on T2 relaxation values in the subtalar joint (both talar and calcaneal articular cartilage), in which the role of compositional quantitative MRI measurement has not been established. Thus, we believe the submitted manuscript is different from the previously published article, which includes some of our study population.

Methodology

• retrospective

• case-control

• performed at one institution

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Copyright information

© European Society of Radiology 2018

Authors and Affiliations

  1. 1.Department of Radiology, Samsung Medical CenterSungkyunkwan University School of MedicineSeoulRepublic of Korea
  2. 2.Department of Health Sciences and TechnologySAIHST, Sungkyunkwan UniversitySeoulKorea
  3. 3.Department of Orthopedic SurgerySamsung Medical Center, Sungkyunkwan University School of MedicineSeoulKorea
  4. 4.Statistics and Data CenterSamsung Medical CenterSeoulKorea

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