Using coronary CT angiography for guiding invasive coronary angiography: potential role to reduce intraprocedural radiation exposure
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We investigated the potential reduction of patient exposure during invasive coronary angiography (ICA) if the procedure had only been directed to the vessel with at least one ≥ 50% stenosis as described in the CT report.
Dose reports of 61 patients referred to ICA because of at least one ≥ 50% stenosis on coronary CT angiography (CCTA) were included. Dose–area product (DAP) was documented separately for left (LCA) and right coronary arteries (RCA) by summing up the single DAP for each angiographic projection. The study population was subdivided as follows: coronary intervention of LCA (group 1) or RCA (group 2) only, or of both vessels (group 3), or further bypass grafting (group 4), or no further intervention (group 5).
57.4% of the study population could have benefitted from reduced exposure if catheterization had been directly guided to the vessel of interest as described on CCTA. Mean relative DAP reductions were as follows: group 1 (n = 18), 11.2%; group 2 (n = 2), 40.3%; group 3 (n = 10), 0%; group 4 (n = 3), 0%; group 5 (n = 28), 28.8%.
Directing ICA to the vessel with stenosis as described on CCTA would reduce intraprocedural patient exposure substantially, especially for patients with single-vessel stenosis.
• Patients with CAD can benefit from decreased radiation exposure during coronary angiography.
• ICA should be directed solely to significant stenoses as described on CCTA.
• Severely calcified plaques remain a limitation of CCTA leading to unnecessary ICA referrals.
KeywordsCoronary vessels Coronary artery disease Coronary angiography Computed tomography angiography Radiation exposure
Coronary artery bypass grafting
Coronary artery disease
Coronary computed tomography angiography
Fractional flow reserve
Invasive coronary angiography
Left coronary artery
Percutaneous coronary intervention
Right coronary artery
The authors state that this work has not received any funding.
Compliance with ethical standards
The scientific guarantor of this publication is Ralf W. Bauer.
Conflict of interest
The authors of this manuscript declare relationships with the following companies:
Ralf W. Bauer is on the speakers’ bureau of Siemens Healthcare, Bayer Healthcare and GE Healthcare. Julian L. Wichmann received speakers’ fees from Siemens Healthcare and GE Healthcare.
Statistics and biometry
One of the authors has significant statistical expertise.
No complex statistical methods were necessary for this paper.
Written informed consent was waived by the institutional review board.
Institutional review board approval was obtained.
• performed at one institution
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