Artifacts during the arterial phase of gadoxetate disodium-enhanced MRI: Multiple arterial phases using view-sharing from two different vendors versus single arterial phase imaging
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To assess the usefulness of multiple arterial phase (AP) of gadoxetic acid-enhanced MRI using view-sharing of two different vendors to reduce transient severe motion (TSM) artifact in the AP.
This retrospective study included 298 patients (mean age 63 years) who underwent gadoxetic acid MRI with multiple AP from two different vendors; either triple (subcohort A, n=174) or quadruple (subcohort B, n=124) AP. 202 patients (143 vs. 59) underwent follow-up MRI with single AP. To compare multiple AP with single AP and between subcohorts, mean artifact score rated by two observers and frequency of significant artifacts were evaluated. Frequency of acquisition of late AP was also assessed.
There was no difference in mean artifact score (p=0.086) or frequency of significant artifacts (p=0.219) between multiple AP and single AP. For the mean best score with multiple AP, subcohort B was better than subcohort A (p<0.001). Late AP was achieved more often with multiple AP (74.8 %, 98.3 %) than with single AP (64.3 %, 64.4 %).
Multiple AP using different view-sharing failed to show differences in TSM artifacts in AP compared to single AP. Frequency of acquisition of late AP was higher with multiple AP. Mean best artifact score of multiple AP is different depending on view-sharing technique.
• TSM artifacts were not significantly different between multiple AP and single AP.
• The frequency of acquiring late AP was higher with multiple AP.
• For multiple APs, TSM artifacts are different according to view-sharing technique.
KeywordsGadoxetic acid Multiple arterial phase Artifact View-sharing Magnetic resonance imaging
Body mass index
Controlled aliasing in parallel imaging results in higher acceleration
Contrast-enhanced time robust angiography
Chronic obstructive pulmonary disease
Magnetic resonance imaging
Time-resolved angiography with keyhole
Transient severe motion
Time-resolved imaging with interleaved stochastic trajectories
Volumetric interpolated breath-hold examination
The authors thank Philips and Siemens Research Laboratories for their technical support and advice to perform this study.
The authors state that this work has not received any funding.
Compliance with ethical standards
The scientific guarantor of this publication is Young Kon Kim in Department of Radiology and Center for Imaging Science, Samsung Medical Centre, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
Conflict of interest
The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
Statistics and biometry
Soohyun Ahn PhD. and Na Young Hwang MS in Biostatistics and Clinical Epidemiology Centre, Research Institute for Future Medicine, Samsung Medical Centre, Seoul, Korea kindly provided statistical advice for this manuscript.
One of the authors has significant statistical expertise.
Institutional Review Board approval was obtained.
Written informed consent was waived by the Institutional Review Board.
• Performed at one institution
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