European Radiology

, Volume 27, Issue 12, pp 5034–5040 | Cite as

Dual energy CT iodine map for delineating inflammation of inflammatory arthritis

  • Takeshi Fukuda
  • Yoshinori Umezawa
  • Akihiko Asahina
  • Hidemi Nakagawa
  • Kazuhiro Furuya
  • Kunihiko Fukuda


Iodine mapping is an image-processing technique used with dual-energy computed tomography (DECT) to improve iodine contrast resolution. CT, because of its high spatial resolution and thin slice reconstruction, is well suited to the evaluation of the peripheral joints. Recent developments in the treatment of inflammatory arthritis that require early diagnosis and precise therapeutic assessment encourage radiological evaluation. To facilitate such assessment, we describe DECT iodine mapping as a novel modality for evaluating rheumatoid arthritis and psoriatic arthritis of the hands and feet.

Key Points

Dual-energy CT iodine mapping can delineate inflammation of peripheral inflammatory arthritis.

DECT iodine mapping has high spatial resolution compared with MRI.

DECT iodine mapping has a high iodine contrast resolution.

DECT iodine mapping may reflect therapeutic effects.


Computed tomography Dual energy Inflammation Arthritis Enthesitis 



We presented a comparison study between contrast-enhanced MRI and DECT iodine mapping at the annual congress of European League Against Rheumatism (EULAR) in 2016. The contents were also published in Radiology (doi:  10.1148/radiol.2016161671).

Compliance with ethical standards


The scientific guarantor of this publication is Takeshi Fukuda.

Conflict of interest

The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.


The authors state that this work has not received any funding.

Statistics and biometry

No complex statistical methods were necessary for this paper.

Informed consent

Written informed consent was obtained from all subjects (patients) in this study.

Ethical approval

Institutional Review Board approval was obtained.


• retrospective

• observational

• performed at one institution


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Copyright information

© European Society of Radiology 2017

Authors and Affiliations

  1. 1.Department of RadiologyThe Jikei University School of MedicineTokyoJapan
  2. 2.Department of DermatologyThe Jikei University School of MedicineTokyoJapan
  3. 3.Division of Rheumatology Department of Internal MedicineThe Jikei University School of MedicineTokyoJapan

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