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CT and MR imaging features of mucinous tubular and spindle cell carcinoma of the kidneys. A multi-institutional review

Abstract

Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney is a recently identified renal malignancy. Diagnosis of this rare subtype of renal tumour can be challenging for pathologists, and as such, any additional data would be helpful to improve diagnostic reliability. As imaging features of this new and rare sub-type have not yet been clearly described, the purpose of this study was to describe the main radiologic features on computed tomography (CT) and magnetic resonance imaging (MRI), based jointly on the literature and findings from a multi-institutional retrospective review of pathology and imaging databases. Using a combination of CT/MRI features, diagnosis of MTSCC could be suggested in many cases. A combination of slow enhancement with plateau on dynamic contrast-enhanced CT/MRI, intermediate to high T2 signal intensity contrasting with low apparent diffusion coefficient values on MRI appeared evocative of this diagnosis.

Key Points

A slow enhancement with plateau is observed either on CT or MRI.

High T2 signal components but low apparent coefficient diffusion are evocative.

T2-weighted imaging features depend on the mucin components of the tumour.

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Abbreviations

ADC:

apparent diffusion coefficient

CEUS:

contrast-enhanced ultrasound

CT:

computed tomography

DCE:

dynamic contrast-enhanced

GE:

gradient echo

Gd:

gadolinium

MR:

magnetic resonance

MTSCC:

mucinous tubular and spindle cell carcinoma

RCC:

renal cell carcinoma

ROI:

region of interest

US:

ultrasound

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Acknowledgments

The scientific guarantor of this publication is Pr Nicolas Grenier. The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. The authors state that this work has not received any funding. No complex statistical methods were necessary for this paper. Institutional Review Board approval was obtained. Written informed consent was waived by the Institutional Review Board. Methodology: retrospective, observational, multicenter study.

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Correspondence to F. Cornelis.

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Cornelis, F., Ambrosetti, D., Rocher, L. et al. CT and MR imaging features of mucinous tubular and spindle cell carcinoma of the kidneys. A multi-institutional review. Eur Radiol 27, 1087–1095 (2017). https://doi.org/10.1007/s00330-016-4469-1

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  • DOI: https://doi.org/10.1007/s00330-016-4469-1

Keywords

  • Kidney
  • Tumour
  • Magnetic resonance imaging
  • Renal cell carcinoma
  • Mucinous tubular and spindle cell carcinoma of kidney