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European Radiology

, Volume 26, Issue 9, pp 2908–2914 | Cite as

Microanatomy of the subcallosal artery: an in-vivo 7 T magnetic resonance angiography study

  • Toshinori MatsushigeEmail author
  • Bixia Chen
  • Philipp Dammann
  • Sören Johst
  • Harald H. Quick
  • Mark E. Ladd
  • Michael Forsting
  • Ulrich Sure
  • Karsten H. Wrede
Magnetic Resonance

Abstract

Objectives

To investigate in-vivo microanatomy of the subcallosal artery branching from the anterior communicating artery (ACoA) using time-of-flight (TOF) magnetic resonance angiography (MRA) at 7 Tesla.

Methods

Seventy-five subjects, including 15 healthy volunteers and 60 patients, were included in this prospective study. Three raters characterized branches from ACoA in maximum intensity projections of TOF MRA at 7 Tesla acquired with 0.22 × 0.22 × 0.41 mm3 resolution. Furthermore, course patterns and anatomical features of the subcallosal artery (maximum diameter, length, and branching angle from ACoA) were measured.

Results

Branches from the anterior communicating artery were visualized in 63 of 74 (85.1 %) subjects and were identified as the subcallosal artery (93.7 %) and the accessory anterior cerebral artery (6.3 %). The course of the subcallosal artery was classified into 3 groups; C-shaped (55.9 %), straight (16.9 %), and S-shaped (27.2 %). There was a significant difference between the branching angles of C-shaped and straight (p < 0.0001), between C-shaped and S-shaped (p < 0.0001), as well as between straight and S-shaped (p = 0.0113) course patterns.

Conclusions

High-resolution in-vivo 7 T TOF MRA can delineate the microanatomy of the subcallosal artery. Three main variants of course patterns and branching angles from ACoA could be identified.

Key Points

In-vivo 7 Tesla TOF MRA can delineate the subcallosal artery microanatomy

Three distinct course patterns of the subcallosal artery were identified

Branching angles from ACoA significantly differed between subcallosal artery course patterns

Keywords

Anatomy Subcallosal artery Anterior communicating artery TOF MRA 7 Tesla 

Notes

Acknowledgments

The authors would like to thank Lena C. Schäfer (RT) for performing all the 7 Tesla examinations. The scientific guarantor of this publication is Dr. Karsten H Wrede. The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. This study has received funding by University Duisburg Essen (IFORES grant). No complex statistical methods were necessary for this paper. Institutional Review Board approval was obtained. Written informed consent was obtained from all subjects (patients) in this study. Methodology: prospective, observational, multicenter study.

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Copyright information

© European Society of Radiology 2015

Authors and Affiliations

  • Toshinori Matsushige
    • 1
    • 2
    • 3
    Email author
  • Bixia Chen
    • 1
    • 3
  • Philipp Dammann
    • 1
    • 3
  • Sören Johst
    • 3
  • Harald H. Quick
    • 3
    • 4
  • Mark E. Ladd
    • 3
    • 5
  • Michael Forsting
    • 6
  • Ulrich Sure
    • 1
  • Karsten H. Wrede
    • 1
    • 3
  1. 1.Department of NeurosurgeryUniversity Hospital Essen, University Duisburg-EssenEssenGermany
  2. 2.Department of Neurosurgery, Graduate School of Biomedical and Health SciencesHiroshima UniversityHiroshimaJapan
  3. 3.Erwin L. Hahn Institute for Magnetic Resonance ImagingUniversity Duisburg-EssenEssenGermany
  4. 4.High Field and Hybrid MR ImagingUniversity Hospital EssenEssenGermany
  5. 5.Division of Medical Physics in RadiologyGerman Cancer Research CenterHeidelbergGermany
  6. 6.Department of Diagnostic and Interventional Radiology and NeuroradiologyUniversity Hospital EssenEssenGermany

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