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Table 2 Subject characteristics and CMR parameters

From: Characterisation of cardiomyopathy by cardiac and aortic magnetic resonance in patients new to hemodialysis

  HD (n = 54) Controls (n = 29) p value
 Age (years) 57 ± 15 56 ± 17 0.7
 Female (%) 15 (28) 8 (28) 1
Anthropometric variables
 Body mass index (kg/m2) 28 ± 6 27 ± 3 0.5
 Body surface area(m2) 1.9 ± 0.2 1.9 ± 0.2 0.9
Medical history
 Time since commenced HD (days) 94 ± 84   
 Diabetes mellitus (%) 14 (26) 2 (7)  
 Ischaemic heart disease (%) 13 (24) 0 (0)  
 Current/ex-smoker (%) 25 (46) 8 (28)  
 Peripheral vascular disease/stroke (%) 7 (13) 0 (0)  
 LV systolic dysfunction (%) 4 (7) 0 (0)  
Medication
 Treated hypertension (%) 42 (78) 2 (7)  
 RAAS antagonist (%) 14 (26) 1 (3)  
 Beta blocker (%) 19 (35) 0 (0)  
 Other antihypertensive (%) 37 (69) 2 (7)  
 Statin use (%) 23 (43) 4 (14)  
CMR parameters
 Global peak systolic strain (%) 15.9 ± 3.7 19.3 ± 3.4 <0.001
 Basal peak systolic strain (%) 14.5 ± 3.8 18.4 ± 4.5 <0.001
 Mid-ventricular peak systolic strain(%) 16.2 ± 4 20 ± 4.2 <0.001
 Apical peak systolic strain (%) 16.9 ± 4.1 19.7 ± 3.4 0.002
 Peak diastolic strain rate (s-1) 1.07 ± 0.33 1.31 ± 0.38 0.003
 Peak systolic strain rate (s-1) 1.03 ± 0.22 1.28 ± 0.24 0.006
 LV dyssynchrony by SD-TTP (ms) 56 ± 21 39 ± 14 <0.001
 LV end-diastolic volume index (ml/m2)* 88 ± 23 75 ± 14 0.002
 LV stroke volume index (ml/m2)* 44 ± 12 44 ± 9 0.8
 LV ejection fraction (%) 51 ± 10 59 ± 5 <0.001
 LV mass index(g/m2)* 63 [54, 79] 46 [42, 53] <0.001
 LV mass/volume ratio (g/ml) 0.76 [0.64, 0.86] 0.65 [0.55, 0.71] 0.001
 Aortic distensibility (mmHg−1 × 10−3) 2 [1.3, 3.1] 4.1 [3.1, 6.2] <0.001
 Aortic pulse wave velocity (m/s) 7.9 ± 3.5 5.3 ± 1.9 0.03
 Systolic blood pressure (mmHg) 143 ± 27 139 ± 18 0.6
 Diastolic blood pressure (mmHg) 76 ± 12 80 ± 10 0.2
 Pulse pressure (mmHg) 61 [50, 79] 60 [48, 68] 0.3
  1. Categorical data are displayed as counts (percentages). Continuous data were tested for normality and summarized as mean ± SD or median [25th, 75th percentile]. HD, haemodialysis; LV, left ventricular; RAAS, renin-angiotensin aldosterone system; SD-TTP standard deviation of time-to-peak strain.*Values indexed to body surface area.