European Radiology

, Volume 23, Issue 7, pp 1901–1910 | Cite as

Prospective evaluation of magnetic resonance enterography for the detection of mesenteric small bowel tumours

  • Elisa Amzallag-BellengerEmail author
  • Philippe Soyer
  • Coralie Barbe
  • Marie-Danièle Diebold
  • Guillaume Cadiot
  • Christine Hoeffel



To prospectively evaluate magnetic resonance (MR) enterography for detecting mesenteric small-bowel tumours (MSBTs) and assess the added value of gadolinium-chelate injection.

Material and methods

Over a 2-year period MR enterography examinations of 75 patients (33 men, 42 women; mean age, 53.8 years; range, 19–85) with suspected MSBT were blindly analysed by two readers for the presence of MSBT. Sensitivities, specificities, predictive positive values (PPVs), negative predictive values (NPVs) and accuracies of MR enterography for the detection of MSBT were calculated on per-patient and per-lesion bases. The McNemar test was used to compare sensitivities and specificities of the unenhanced and gadolinium-enhanced sets of MR enterographies.


Thirty-seven MSBTs were pathologically confirmed in 26 patients. The mean tolerance score of the examinations was 0.7. On a per-patient basis, sensitivity, specificity, PPV, NPV and accuracy for detection of MSBT were 96 % [95 % CI, 89–100 %], 96 % [90–100 %], 93 % [83–100 %], 98 % [94–100 %] and 96 % [92–100 %], respectively. On a per-lesion basis, sensitivity and PPV were 70 % [56–85 %] and 93 % [83–100 %], respectively. Gadolinium injection yielded higher sensitivities on both bases (P = 0.008).


MR enterography is an accurate and well-tolerated imaging modality for detecting MSBT. Intravenous administration of gadolinium-chelate improves sensitivity for MSBT detection.

Key Points

• MR enterography accurately detects mesenteric small bowel tumours.

• MR enterography is a well-tolerated imaging technique.

• Intravenous administration of gadolinium chelate improves sensitivity for detecting small-bowel tumours.


MR imaging MR enterography Small-bowel tumours Tumour Gadolinium 



Mesenteric small-bowel tumour


Videocapsule endoscopy


Polyethylene glycol


Half-Fourier single-shot spin echo


True free-induction with steady state free precession


Volumetric interpolated breath-hold


Gastrointestinal stromal tumour


Peutz-Jeghers syndrome



The authors did not receive any support for this article.

G. Cadiot is a board member of Mayoli Spindler and is a consultant for Novartis and Kéocyt; he has received payments for lectures, including service on speakers bureaus, from Ipsen, Novartis, Biocodex, Abbott and Mayoli Spindler, for manuscript preparation from Novartis and for the development of educational presentations from Pfizer and Ipsen; he has also received travel, accommodation and meeting expenses from Ferring.


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Copyright information

© European Society of Radiology 2013

Authors and Affiliations

  • Elisa Amzallag-Bellenger
    • 1
    Email author
  • Philippe Soyer
    • 2
    • 3
  • Coralie Barbe
    • 4
  • Marie-Danièle Diebold
    • 5
  • Guillaume Cadiot
    • 6
  • Christine Hoeffel
    • 1
  1. 1.Department of RadiologyHôpital Robert DebréReims CedexFrance
  2. 2.Department of RadiologyHôpital Lariboisière, Assistance Publique-Hôpitaux de ParisParisFrance
  3. 3.Université Paris-Diderot, Sorbonne Paris CitéParisFrance
  4. 4.Department of StatisticsHôpital Robert DebréReims CedexFrance
  5. 5.Department of PathologyHôpital Robert DebréReims CedexFrance
  6. 6.Department of GastroenterologyHôpital Robert DebréReims CedexFrance

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