To evaluate the features of stent gap (SG) and the long-term impact of SG on in-stent restenosis (ISR) in patent stents.
A total of 347 consecutive patients with 781 stents who underwent MDCT were assessed for SG and ISR. Clinical and stent features were compared between the SG and non-SG groups. In the follow-up study, among 82 patients with 175 patent stents [26 assessed by conventional coronary angiography (CCA) including 6 contacted in a telephone survey, 46 assessed by computed tomography angiography (CTA) and 10 by both], the incidence of ISR was compared between stents with and without SG.
Three patients and 13 stents were excluded. SG was observed in 12.5% of patients and 8.6% of stents. ISR detected by CTA was noted in 21.2% of SG, and SG accounted for 23.7% of ISR. Stent number, length, location, overlapping pattern, tortuosity and in-out angle were predisposing factors for SG. During a mean follow-up period of 15 months after detection of SG, the incidence of ISR was significantly higher in the SG group than in the non-SG group (43.8/14.9% by CCA, 33.3/10.1% by CTA and CCA).
Patent stents with SG detected by CTA had a higher incidence of late restenosis, indicating that long-term follow-up or further intervention is necessary.
• Coronary artery computed tomographic angiography (CTA) is increasingly used following coronary intervention.
• Gaps within coronary stents detected by CTA correlate with in-stent restenosis.
• Patients with stent gaps have more late restenosis at follow-up.
• More attention should be given to patients with stent gaps.
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Computed tomography angiography
Conventional coronary angiography
Multi-detector computed tomography
Maximum intensity projection
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The authors would like to thank Dr. Chen, Jiuhong, CT Research Collaboration, Healthcare Sector, Siemens Ltd., China, for her assistance with editing. This research was funded by National Key Technology R&D Program of SPRECA-MDCT. The contract grant number is 2007BAI05B02.
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Zhang, X., Yang, L., Ju, H. et al. Prevalence and prognosis of coronary stent gap detected by multi-detector CT: a follow-up study. Eur Radiol 22, 1896–1903 (2012). https://doi.org/10.1007/s00330-012-2458-6
- X-ray computed tomography
- Coronary restenosis
- Coronary angiography