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Identification and further differentiation of subendocardial and transmural myocardial infarction by fast strain-encoded (SENC) magnetic resonance imaging at 3.0 Tesla

  • Magnetic Resonance
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Abstract

Objectives

To investigate whether subendocardial and transmural myocardial infarction can be identified and differentiated using the peak circumferential and longitudinal strains measured by fast strain-encoded (SENC).

Methods

Nineteen patients with ischemic heart diseases underwent imaging with fast SENC and late gadolinium enhancement (LGE) MRI at 3 T. Fast SENC measurements were performed in three short-axis slices (basal, mid-ventricular and apical levels) and one long-axis view (four-chamber) to assess peak longitudinal and circumferential systolic strains.

Results

All patients showed myocardial infarction with an average of 7 positive LGE segments. A total of 304 segments for longitudinal strains (LS) and 114 segments for circumferential strains (CS) could be analysed. Positive LGE segments showed lower peak CS and LS compared with the no LGE segments (P < 0.0001 for both). Segments with subendocardial infarction showed reduced CS and LS compared with the no LGE segments (P < 0.0001 for both). There was a significant difference in CS between subendocardial and transmural infarct segments (P = 0.03), but no significant difference in LS between them (P = 0.64).

Conclusions

Fast SENC can identify old myocardial infarction and differentiate subendocardial from transmural infarction.

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Acknowledgements

This research was presented at the ECR 2010 in Vienna and was awarded the certificate of merit.

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Authors and Affiliations

  1. Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Kita15, Nishi 7, kita-ku, Sapporo, Japan, 060–8638

    Noriko Oyama-Manabe, Hiroyuki Sugimori, Tamotsu Kamishima, Khin Khin Tha, Satoshi Terae & Hiroki Shirato

  2. Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan

    Naoki Ishimori & Hiroyuki Tsutsui

  3. MR Clinical Science, Philips Healthcase, Tokyo, Japan

    Marc Van Cauteren & Tomoyuki Okuaki

  4. Advanced Medical Research Center, Iwate Medical University, Morioka, Japan

    Kohsuke Kudo

  5. Department of Nuclear Medicine, Hokkaido University Hospital, Sapporo, Japan

    Osamu Manabe

  6. Hokkaido Organization for Translational Research, Hokkaido University Graduate School of Medicine, Sapporo, Japan

    Yoichi M. Ito

Authors
  1. Noriko Oyama-Manabe
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  2. Naoki Ishimori
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  3. Hiroyuki Sugimori
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  8. Tamotsu Kamishima
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  9. Yoichi M. Ito
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  10. Hiroyuki Tsutsui
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  11. Khin Khin Tha
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  12. Satoshi Terae
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  13. Hiroki Shirato
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Corresponding author

Correspondence to Noriko Oyama-Manabe.

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Oyama-Manabe, N., Ishimori, N., Sugimori, H. et al. Identification and further differentiation of subendocardial and transmural myocardial infarction by fast strain-encoded (SENC) magnetic resonance imaging at 3.0 Tesla. Eur Radiol 21, 2362–2368 (2011). https://doi.org/10.1007/s00330-011-2177-4

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  • DOI: https://doi.org/10.1007/s00330-011-2177-4

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