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European Radiology

, Volume 21, Issue 8, pp 1594–1599 | Cite as

Prevalence of enlarged mediastinal lymph nodes in heavy smokers—a comparative study

  • Johannes KirchnerEmail author
  • Esther Maria Kirchner
  • Jan Peter Goltz
  • Vivian-Wilma Lorenz
  • Ralph Kickuth
Chest

Abstract

Objective

To evaluate the frequency of enlarged hilar or mediastinal lymph nodes in heavy smokers (more than 10 pack years) compared with non- smokers.

Material and methods

In a prospective study the CT findings of 88 consecutive patients (44 heavy smokers, 44 non- smokers) were analysed. Exclusion criteria were history of thoracic malignancy, sarcoidosis, occupational dust exposure or clinical evidence of pneumonia. Prevalence, size and site of enlarged lymph nodes were assessed by multidetector computed tomography (MDCT) and correlated with the cigarette consumption and the CT- findings of bronchitis and emphysema.

Results

Twenty-three of the 44 heavy smokers (52%) showed enlarged mediastinal lymph nodes. Non- smokers showed enlarged lymph nodes in 9% (4/44). The most common site of enlarged lymph nodes was the regional station 7 according to the ATS mapping (subcarinal). The difference between the frequency of enlarged lymph nodes in heavy smokers and non- smokers was significant (chi- square 19.3, p < 0.0001). Airway wall thickening and emphysema were often associated with an increased number of enlarged nodes.

Conclusion

The present study demonstrates that enlarged mediastinal lymph nodes may occur in a rather high percentage of heavy smokers, especially in those with a MDCT finding of severe bronchitis.

Keywords

Tobacco MDCT Lymph node enlargement Comparative study 

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Copyright information

© European Society of Radiology 2011

Authors and Affiliations

  • Johannes Kirchner
    • 1
    Email author
  • Esther Maria Kirchner
    • 2
  • Jan Peter Goltz
    • 3
  • Vivian-Wilma Lorenz
    • 1
  • Ralph Kickuth
    • 3
  1. 1.Department of Diagnostic and Interventional RadiologyAllgemeines Krankenhaus HagenHagenGermany
  2. 2.Clinic for MedicineStädtisches Klinikum WedauDuisburgGermany
  3. 3.Department of RadiologyUniversity Hospital of WuerzburgWuerzburgGermany

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