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European Radiology

, Volume 20, Issue 9, pp 2194–2199 | Cite as

Magnetic resonance diffusion tensor imaging and tractography of the lower spinal cord: application to diastematomyelia and tethered cord

  • Christopher G. Filippi
  • Trevor Andrews
  • Jay V. Gonyea
  • Grant Linnell
  • Keith A. CauleyEmail author
Neuro

Abstract

Objectives

To investigate the feasibility of routine clinical DTI of the lower spinal cord using high-field-strength MRI and parallel imaging, and to evaluate the utility of diffusion tensor imaging and tractography as tools for study of lower cord pathology.

Methods

Three patients with diastematomyelia, one patient with tethered cord, and six normal volunteers underwent MR imaging of the lower spine at 3 T. A 15-channel spine coil and parallel imaging were used with a six-direction single-shot echo-planar gradient echo technique.

Results

In normal volunteers, tractography delineated the conus and cauda equina. Tractography software permitted assessment of fractional anisotropy of the distal cord and nerve roots. In cases of tethered cord, tractography correlated with anatomical imaging. Tractography also correlated with the anatomical pathological findings in cases of diastematomyelia.

Conclusions

The methods described enable routine DTI and tractography of the lower spinal cord at 3 T. Compared with conventional imaging, tractography offers additional information that may prove useful in the characterization and surgical planning for congenital lesions involving the lower spinal cord.

Keywords

Diffusion tensor imaging Tractography Spinal cord Diastematomyelia Tethered cord 

Notes

Acknowledgements

The authors thank Gretchen White and the MR technology staff of Fletcher Allen Hospital for their help with this work.

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Copyright information

© European Society of Radiology 2010

Authors and Affiliations

  • Christopher G. Filippi
    • 2
  • Trevor Andrews
    • 2
    • 3
  • Jay V. Gonyea
    • 2
  • Grant Linnell
    • 2
  • Keith A. Cauley
    • 1
    Email author
  1. 1.Department of Radiology, Division of NeuroradiologyUniversity of Massachusetts Medical CenterWorcesterUSA
  2. 2.Department of Radiology, Fletcher Allen HealthcareUniversity of Vermont College of MedicineBurlingtonUSA
  3. 3.Philips HealthcareHighland HeightsUSA

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