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Determining gastric cancer resectability by dynamic MDCT

European Radiology volume 20, pages 613–620 (2010)Cite this article

Abstract

Purpose

Multi-detector row CT (MDCT) has been widely used to detect primary lesions and to evaluate TNM staging. In this study we evaluated the accuracy of dynamic MDCT in the preoperative determination of the resectability of gastric cancer.

Methods

MDCT was used to image 350 cases of gastric cancer diagnosed by biopsy before surgery. MDCT findings regarding TNM staging and resectability were correlated with surgical and pathological findings.

Results

The accuracy of MDCT for staging gastric cancer was high, especially for tumour stage T1 (94.3%), lymph node stage N2 (87.3%), and for predicting distant metastases (>96.6%). When resectability was considered to be the outcome, the total accuracy of MDCT was 87.4%, sensitivity was 89.7% and specificity was 76.7%. Results showed high sensitivity for identifying peritoneal seeding (90.0%) and for predicting liver metastasis (80.0%).

Conclusion

Dynamic enhanced MDCT is useful for TNM staging of gastric cancers and for predicting tumour respectability preoperatively.

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Abbreviations

EUS:

endoscopic ultrasound

CT:

computed tomography

LN:

lymph node

MDCT:

multi-detector row CT

MIP:

maximal intensity projection

MPR:

multiplanar reformatting

MRI:

magnetic resonance imaging

TNM:

tumour/node/metastasis

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Acknowledgements

Special thanks to Min Yan, Haipeng Dong, Zhenfang Wu, Weipin Shi, and Heshi Liu from Ruijin Hospital and Jiaotong University for their important contributions.

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Affiliations

  1. Department of Radiology, Ruijin Hospital affiliated to Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China

    Zilai Pan, Huan Zhang, Lianjun Du, Bei Ding, Qi Song, Huawei Ling, Baisong Huang & Kemin Chen

  2. Department of Surgery, Ruijin Hospital affiliated to Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China

    Chao Yan

Authors
  1. Zilai Pan
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  2. Huan Zhang
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  3. Chao Yan
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  4. Lianjun Du
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  5. Bei Ding
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  6. Qi Song
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  7. Huawei Ling
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  8. Baisong Huang
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  9. Kemin Chen
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Correspondence to Huan Zhang.

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Pan, Z., Zhang, H., Yan, C. et al. Determining gastric cancer resectability by dynamic MDCT. Eur Radiol 20, 613–620 (2010). https://doi.org/10.1007/s00330-009-1576-2

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  • DOI: https://doi.org/10.1007/s00330-009-1576-2

Keywords

  • Gastric cancer
  • Multi-detector row CT
  • MDCT
  • Resectability
  • TNM staging