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Usefulness of lesion image mapping with multidetector-row helical computed tomography using a dedicated skin marker in breast-conserving surgery

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Abstract

To investigate the usefulness of computed tomography (CT) with skin-marker placement in determining the excision area and decreasing the positive or close margin rates in breast-conserving surgery (BCS). Multidetector-row helical computed tomography (MDCT) mapping images were reconstructed in subjects (n = 117) diagnosed with primary breast cancer who had undergone MDCT using CT skin markers. Serial 5-mm-thick slices prepared from the surgical specimen were used for pathological analyses. A “positive margin” was defined as the presence of malignant cells at the surgical margin, and a “close margin” as a tumor within 5 mm of the surgical margin. The rates of positive and close margins were calculated. We identified the lesions in 111 of 117 cases (94.9%) on MDCT. Of these, 93 underwent BCS under the guidance of MDCT mapping and the remaining 18 underwent mastectomy. Among the 93 cases, 6 (6.5%) had positive or close margins and were diagnosed with ductal carcinoma in situ of low nuclear grade. MDCT mapping with a CT skin marker is feasible for simulating surgical positioning and determining the excision area. MDCT mapping could decrease the positive and close margin rates in BCS.

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Acknowledgements

We thank the staff at the Department of Radiology for technical assistance in manuscript preparation.

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Authors and Affiliations

  1. Department of Surgical Oncology, Seiryo-machi 1-1, Aoba-ku, Sendai, 980-8574, Japan

    Narumi Harada-Shoji, Takanori Ishida, Masakazu Amari, Akihiko Suzuki & Noriaki Ohuchi

  2. Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine, Seiryo-machi 1-1, Aoba-ku, Sendai, 980-8574, Japan

    Takayuki Yamada

  3. Department of Pathology, Kawasaki Medical School, Matsushima 577, Kurashiki, 701-0192, Japan

    Takuya Moriya

Authors
  1. Narumi Harada-Shoji
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  2. Takayuki Yamada
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  3. Takanori Ishida
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  4. Masakazu Amari
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  5. Akihiko Suzuki
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  6. Takuya Moriya
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  7. Noriaki Ohuchi
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Correspondence to Narumi Harada-Shoji.

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Harada-Shoji, N., Yamada, T., Ishida, T. et al. Usefulness of lesion image mapping with multidetector-row helical computed tomography using a dedicated skin marker in breast-conserving surgery. Eur Radiol 19, 868–874 (2009). https://doi.org/10.1007/s00330-008-1220-6

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  • DOI: https://doi.org/10.1007/s00330-008-1220-6

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