Skip to main content

Advertisement

SpringerLink
Log in

Imaging features of musculoskeletal involvement in systemic sclerosis

  • Musculoskeletal
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

This article describes the radiographic, sonographic and magnetic resonance (MR) features of musculoskeletal involvement in patients with systemic sclerosis (SSc). Conventional radiography is the traditional method of detecting digital calcifications, but ultrasonography (US) is also able to detect such calcifications before they appear on radiographs. MR imaging can be used to diagnose overlapping conditions (i.e., SSc and myositis or SSc and rheumatoid arthritis), and less frequently, to reveal neurologic complications of SSc. In patients with vascular ulcers, MR angiography is able to depict decreased flow within collateral digital arteries.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2a,b
Fig. 3a–d
Fig. 4a,b
Fig. 5a–c
Fig. 6a,b
Fig. 7
Fig. 8a–c
Fig. 9
Fig. 10a–c
Fig. 11a,b
Fig. 12a,b

Similar content being viewed by others

References

  1. Resnick D (1995) Scleroderma (progressive systemic sclerosis). Diagnosis of bone and joint disorders, 3rd edn. Saunders, Philadelphia, pp 1191–1217

  2. Jimenez SA, Derk CT (2004) Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis. Ann Intern Med 140:37–50

    PubMed  CAS  Google Scholar 

  3. (1980) Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum 23:581–590

  4. Spencer-Green G, Alter D, Welch HG (1997) Test performance in systemic sclerosis: anti-centromere and anti-Scl-70 antibodies. Am J Med 103:242–248

    Article  PubMed  CAS  Google Scholar 

  5. LeRoy EC, Medsger TA Jr (2001) Criteria for the classification of early systemic sclerosis. J Rheumatol 28:1573–1576

    PubMed  CAS  Google Scholar 

  6. Lonzetti LS, Joyal F, Raynauld JP et al (2001) Updating the American College of Rheumatology preliminary classification criteria for systemic sclerosis: addition of severe nailfold capillaroscopy abnormalities markedly increases the sensitivity for limited scleroderma. Arthritis Rheum 44:735–736

    Article  PubMed  CAS  Google Scholar 

  7. Poormoghim H, Lucas M, Fertig N, Medsger TA Jr (2000) Systemic sclerosis sine scleroderma: demographic, clinical, and serologic features and survival in forty-eight patients. Arthritis Rheum 43:444–451

    Article  PubMed  CAS  Google Scholar 

  8. Lally EV, Jimenez SA, Kaplan SR (1988) Progressive systemic sclerosis: mode of presentation, rapidly progressive disease course, and mortality based on an analysis of 91 patients. Semin Arthritis Rheum 18:1–13

    Article  PubMed  CAS  Google Scholar 

  9. Pope JE (2003) Musculoskeletal involvement in scleroderma. Rheum Dis Clin North Am 29:391–408

    Article  PubMed  Google Scholar 

  10. Lomeo RM, Cornella RJ, Schabel SI, Silver RM (1989) Progressive systemic sclerosis sine scleroderma presenting as pulmonary interstitial fibrosis. Am J Med 87:525–527

    Article  PubMed  CAS  Google Scholar 

  11. De Villiers WJS, Jardann HF, Bates W (1992) Systemic sclerosis sine scleroderma presenting with vitiligo-like depigmentation and interstitial pulmonary fibrosis. Clin Exp Dermatol 17:127–131

    Article  PubMed  Google Scholar 

  12. Molina JF, Anaya JM, Cabrera GE, Hoffman E, Espinoza LR (1995) Systemic sclerosis sine scleroderma: an unusual presentation in scleroderma renal crisis. J Rheumatol 22:557–560

    PubMed  CAS  Google Scholar 

  13. Ojemann JG, Grubb RL, Kyriakos M, Baker KB (1997) Calcium carbonate apatite deposition in the cervical spine with associated vertebral destruction. Case report. J Neurosurg 86:1022–1026

    Article  PubMed  CAS  Google Scholar 

  14. Arginteanu MS, Perin NI (1997) Paraspinal calcinosis associated with progressive systemic sclerosis. Case report. J Neurosurg 87:761–763

    PubMed  CAS  Google Scholar 

  15. Olsen KM, Pike EJ, Chew FS (2004) Progressive systemic sclerosis with massive paraspinal soft-tissue calcinosis. AJR Am J Roentgenol 183:634

    PubMed  Google Scholar 

  16. Teng AL, Robbin MR, Furey CG, Easley SE, Abdul-Karim FW, Bohlman HH (2006) Tumoral calcinosis in the cervical spine in a patient with CREST syndrome. A case report. J Bone Joint Surg Am 88:193–197

    Article  PubMed  Google Scholar 

  17. Petrocelli AR, Bassett LW, Mirra J, Gold RH, Brahn E (1988) Scleroderma: dystrophic calcification with spinal cord compression. J Rheumatol 15:1733–1735

    PubMed  CAS  Google Scholar 

  18. Clements PJ, Furst DE, Campion DS et al (1988) Muscle disease in progressive systemic sclerosis. Diagnostic and therapeutic considerations. Arthritis Rheum 21:62

    Article  Google Scholar 

  19. Hachulla E, Dubucquoi S (2004) Nuclear auto-antibodies: a useful tool for the diagnosis, the classification and the prognosis of systemic sclerosis. Rev Med Interne 25:442–447

    PubMed  CAS  Google Scholar 

  20. Brun B, Serup J, Hagdrup H (1983) Radiological changes of the hands in systemic sclerosis. Acta Derm Venereol 63:349

    PubMed  CAS  Google Scholar 

  21. Block JA, Sequeira W (2001) Raynaud’s phenomenon. Lancet 357:2042–2048

    Article  PubMed  CAS  Google Scholar 

  22. Cutolo M, Sulli A, Pizzorni C, Accardo S (2000) Nailfold videocapillaroscopy assessment of microvascular damage in systemic sclerosis. J Rheumatol 27:155–160

    PubMed  CAS  Google Scholar 

  23. Cazalets C, Cador B, Rolland Y et al (2004) Digital flow exploration by color Doppler ultrasound in patients with Raynaud’s disease or systemic sclerosis. J Mal Vasc 29:12–20

    Article  PubMed  CAS  Google Scholar 

  24. Stucker M, Quinna S, Memmel U et al (2000) Macroangiopathy of the upper extremities in progressive systemic sclerosis. Eur J Med Res 5:295–302

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Musculoskeletal Radiology, Hôpital Roger Salengro, CHRU de Lille, Boulevard du Pr. J Leclercq, 59037, Lille Cedex, France

    Nathalie Boutry, Claire Zanetti-Musielak, Mélanie Morel, Xavier Demondion & Anne Cotten

  2. Department of Internal Medicine, National Scleroderma Center, Centre Hospitalier Universitaire de Lille, Lille Cedex, France

    Éric Hachulla

  3. Department of Anatomy, Centre Hospitalier Universitaire de Lille, Lille Cedex, France

    Xavier Demondion

Authors
  1. Nathalie Boutry
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Éric Hachulla
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Claire Zanetti-Musielak
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Mélanie Morel
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Xavier Demondion
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Anne Cotten
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Nathalie Boutry.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Boutry, N., Hachulla, É., Zanetti-Musielak, C. et al. Imaging features of musculoskeletal involvement in systemic sclerosis. Eur Radiol 17, 1172–1180 (2007). https://doi.org/10.1007/s00330-006-0420-1

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00330-006-0420-1

Keywords

Search

Navigation