European Radiology

, Volume 17, Issue 1, pp 33–38 | Cite as

Long term evaluation of brain perfusion with magnetic resonance in high flow extracranial-intracranial saphenous graft bypass

  • Alessandro BozzaoEmail author
  • Fabrizio Fasoli
  • Vanina Finocchi
  • Giuseppe Santoro
  • Andrea Romano
  • Luigi Maria Fantozzi


Assessment was made of the cerebral vascular haemodynamic parameters in patients with a high-flow extra-intracranial (EC-IC) bypass performed for therapeutic occlusion of the internal carotid artery (ICA). Sixteen patients with ICA occlusion and EC-IC bypass (time interval from surgery 1–6 years) underwent MRI. Perfusion-weighted magnetic resonance imaging (PW-MRI) sequences were performed without the use of an arterial input function. The relative cerebral blood volume (rCBV), mean transit time (MTT) and relative cerebral blood flow (rCBF) were evaluated in all patients at the level of the basal ganglia, centrum semiovale and cortex in both hemispheres. Statistically significant differences (P<0.005) were observed in the haemodynamic parameters, indicating increased rCBV in the basal ganglia and decreased rCBF and rCBV in the cortex of the hemisphere supplied by the graft with respect to the contralateral. Patients with occlusion of the ICA and high flow EC-IC bypass do have altered vascular haemodynamic status between the hemispheres. In particular, rCBF is impaired in the surgical hemisphere at the level of the cortex. These patients should be followed-up to rule out chronic ischemia.


Brain Extra-intracranial by-pass Carotid occlusion Brain aneurysms Perfusion-weighted imaging 


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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Alessandro Bozzao
    • 1
    • 3
    Email author
  • Fabrizio Fasoli
    • 1
  • Vanina Finocchi
    • 1
  • Giuseppe Santoro
    • 2
  • Andrea Romano
    • 1
  • Luigi Maria Fantozzi
    • 1
  1. 1.Department of Neuroradiology, II Faculty of MedicineUniversity of Rome La SapienzaRomeItaly
  2. 2.Department of Neurosurgery, I Faculty of MedicineUniversity of Rome La SapienzaRomeItaly
  3. 3.Sant’Andrea HospitalRomeItaly

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